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    Tnfrsf17 tumor necrosis factor receptor superfamily, member 17 [ Mus musculus (house mouse) ]

    Gene ID: 21935, updated on 27-Nov-2024

    Summary

    Official Symbol
    Tnfrsf17provided by MGI
    Official Full Name
    tumor necrosis factor receptor superfamily, member 17provided by MGI
    Primary source
    MGI:MGI:1343050
    See related
    Ensembl:ENSMUSG00000022496 AllianceGenome:MGI:1343050
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BCM; BCMA; Tnfrsf13; Tnfrsf13a
    Summary
    Predicted to enable signaling receptor activity. Acts upstream of or within lymphocyte homeostasis. Predicted to be located in membrane. Is expressed in several structures, including hemolymphoid system gland; hippocampus; male reproductive gland or organ; superior cervical ganglion; and urinary system. Human ortholog(s) of this gene implicated in colon carcinoma and multiple myeloma. Orthologous to human TNFRSF17 (TNF receptor superfamily member 17). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in large intestine adult (RPKM 2.7), duodenum adult (RPKM 1.8) and 10 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Tnfrsf17 in Genome Data Viewer
    Location:
    16 A1; 16 6.42 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (11131131..11137938)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (11313232..11320074)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E8617 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:11254345-11254532 Neighboring gene G1 to S phase transition 1 Neighboring gene predicted gene, 57631 Neighboring gene microRNA 1945 Neighboring gene STARR-seq mESC enhancer starr_40101 Neighboring gene STARR-positive B cell enhancer mm9_chr16:11322815-11323116 Neighboring gene sorting nexin 29 Neighboring gene STARR-positive B cell enhancer mm9_chr16:11385888-11386189 Neighboring gene STARR-positive B cell enhancer ABC_E5524 Neighboring gene STARR-positive B cell enhancer ABC_E1181 Neighboring gene DEAH (Asp-Glu-Ala-His) box polypeptide 15 pseudogene Neighboring gene STARR-seq mESC enhancer starr_40106 Neighboring gene tyrosine-protein kinase SgK223 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (4) 
    • Targeted (4)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in adaptive immune response IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within lymphocyte homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in tumor necrosis factor-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    tumor necrosis factor receptor superfamily member 17
    Names
    B-cell maturation protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011608.1NP_035738.1  tumor necrosis factor receptor superfamily member 17

      See identical proteins and their annotated locations for NP_035738.1

      Status: PROVISIONAL

      Source sequence(s)
      AF061505
      Consensus CDS
      CCDS27962.1
      UniProtKB/Swiss-Prot
      O88472
      Related
      ENSMUSP00000023140.6, ENSMUST00000023140.6
      Conserved Domains (1) summary
      cd13414
      Location:1165
      TNFRSF17; Tumor necrosis factor receptor superfamily member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA), as well as TNFRSF13A

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      11131131..11137938
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006521990.4XP_006522053.1  tumor necrosis factor receptor superfamily member 17 isoform X2

      Conserved Domains (2) summary
      cd00185
      Location:118
      TNFRSF; CRD1 [structural motif]
      cl22855
      Location:1112
      TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)
    2. XM_006521989.5XP_006522052.1  tumor necrosis factor receptor superfamily member 17 isoform X1

      Conserved Domains (1) summary
      cd13414
      Location:1161
      TNFRSF17; Tumor necrosis factor receptor superfamily member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA), as well as TNFRSF13A