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    Cfap161 cilia and flagella associated protein 161 [ Mus musculus (house mouse) ]

    Gene ID: 75556, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cfap161provided by MGI
    Official Full Name
    cilia and flagella associated protein 161provided by MGI
    Primary source
    MGI:MGI:1922806
    See related
    Ensembl:ENSMUSG00000011154 AllianceGenome:MGI:1922806
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700026D08Rik
    Summary
    Involved in flagellated sperm motility. Is active in axonemal A tubule inner sheath and sperm flagellum. Is expressed in several structures, including brain; genitourinary system; lung; node; and sensory organ. Orthologous to human CFAP161 (cilia and flagella associated protein 161). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in testis adult (RPKM 6.8) and ovary adult (RPKM 0.3) See more
    Orthologs
    NEW
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    Genomic context

    See Cfap161 in Genome Data Viewer
    Location:
    7 D3; 7 47.74 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (83424820..83447528, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (83775612..83798025, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene interleukin 16 Neighboring gene 3-phosphoglycerate dehydrogenase, pseudogene 1 Neighboring gene heterogeneous nuclear ribonucleoprotein K pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E9695 Neighboring gene STARR-seq mESC enhancer starr_19410 Neighboring gene STARR-seq mESC enhancer starr_19411 Neighboring gene VISTA enhancer mm729 Neighboring gene predicted gene, 39043 Neighboring gene STARR-seq mESC enhancer starr_19412 Neighboring gene RIKEN cDNA 3110009M11 gene Neighboring gene STARR-seq mESC enhancer starr_19413

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (2)  1 citation

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in flagellated sperm motility IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in axonemal A tubule inner sheath IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in axonemal microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    located_in axonemal microtubule ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in motile cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in sperm flagellum IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    cilia- and flagella-associated protein 161

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029335.3NP_083611.2  cilia- and flagella-associated protein 161

      See identical proteins and their annotated locations for NP_083611.2

      Status: VALIDATED

      Source sequence(s)
      AC116389, AK006375, AW047638, EU234011
      Consensus CDS
      CCDS21413.1
      UniProtKB/Swiss-Prot
      Q6P8Y0, Q9D9X1
      UniProtKB/TrEMBL
      D3YVU5
      Related
      ENSMUSP00000011298.8, ENSMUST00000011298.14

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      83424820..83447528 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017312364.2XP_017167853.1  cilia- and flagella-associated protein 161 isoform X2

      UniProtKB/TrEMBL
      C6EQH5
    2. XM_006508291.4XP_006508354.1  cilia- and flagella-associated protein 161 isoform X1

      See identical proteins and their annotated locations for XP_006508354.1

      UniProtKB/Swiss-Prot
      Q6P8Y0, Q9D9X1
      UniProtKB/TrEMBL
      D3YVU5