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    Tma16 translation machinery associated 16 [ Mus musculus (house mouse) ]

    Gene ID: 66282, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tma16provided by MGI
    Official Full Name
    translation machinery associated 16provided by MGI
    Primary source
    MGI:MGI:1913532
    See related
    Ensembl:ENSMUSG00000025591 AllianceGenome:MGI:1913532
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1810029B16Rik
    Summary
    Predicted to enable preribosome binding activity. Predicted to be involved in ribosomal large subunit biogenesis. Predicted to be located in nucleolus and nucleoplasm. Predicted to be active in nucleus. Is expressed in liver lobe and urethra. Orthologous to human TMA16 (translation machinery associated 16 homolog). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in CNS E11.5 (RPKM 3.1), CNS E14 (RPKM 2.3) and 24 other tissues See more
    Orthologs
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    Genomic context

    See Tma16 in Genome Data Viewer
    Location:
    8 B3.1; 8 33.14 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (66928995..66939182, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (66476343..66486530, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene membrane associated ring-CH-type finger 1 Neighboring gene predicted gene, 26123 Neighboring gene STARR-seq mESC enhancer starr_21667 Neighboring gene predicted gene, 24205 Neighboring gene STARR-seq mESC enhancer starr_21668 Neighboring gene STARR-seq mESC enhancer starr_21669 Neighboring gene STARR-seq mESC enhancer starr_21670 Neighboring gene STARR-seq mESC enhancer starr_21671 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:69010363-69010546 Neighboring gene STARR-seq mESC enhancer starr_21673 Neighboring gene predicted gene, 32568 Neighboring gene transketolase-like 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    enables preribosome binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables preribosome binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in ribosomal large subunit biogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in ribosomal large subunit biogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    translation machinery-associated protein 16
    Names
    UPF0534 protein C4orf43 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357208.1NP_001344137.1  translation machinery-associated protein 16 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC122800, AK031875, BC016246
      Conserved Domains (1) summary
      pfam11176
      Location:399
      Tma16; Translation machinery-associated protein 16
    2. NM_025465.3NP_079741.1  translation machinery-associated protein 16 isoform 1

      See identical proteins and their annotated locations for NP_079741.1

      Status: VALIDATED

      Source sequence(s)
      AC122800, AK031875, BC034844, BF020125
      Consensus CDS
      CCDS40353.1
      UniProtKB/Swiss-Prot
      Q05DD8, Q9CR02
      Related
      ENSMUSP00000026681.6, ENSMUST00000026681.7
      Conserved Domains (1) summary
      pfam11176
      Location:13161
      DUF2962; Protein of unknown function (DUF2962)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      66928995..66939182 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)