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    dhs-6 Hydroxysteroid dehydrogenase-like protein 2 [ Caenorhabditis elegans ]

    Gene ID: 3565470, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dhs-6
    Official Full Name
    Hydroxysteroid dehydrogenase-like protein 2
    Primary source
    WormBase:WBGene00000970
    Locus tag
    CELE_C17G10.8
    See related
    AllianceGenome:WB:WBGene00000970
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable oxidoreductase activity. Predicted to be located in peroxisome. Predicted to be active in mitochondrion. Orthologous to human HSDL2 (hydroxysteroid dehydrogenase like 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See dhs-6 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    6
    Sequence:
    Chromosome: II; NC_003280.10 (5617128..5619319, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Transmembrane protein Neighboring gene Eukaryotic translation initiation factor 3 subunit L Neighboring gene Nuclear protein localization protein 4 homolog 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The CeCDC-14 phosphatase is required for cytokinesis in the Caenorhabditis elegans embryo. Gruneberg U, et al. J Cell Biol, 2002 Sep 2. PMID 12213836, Free PMC Article
    2. Voltage-dependent anion channel (VDAC-1) is required for olfactory sensing in Caenorhabditis elegans. Uozumi T, et al. Genes Cells, 2015 Oct. PMID 26223767
    3. Sperm chromatin proteomics identifies evolutionarily conserved fertility factors. Chu DS, et al. Nature, 2006 Sep 7. PMID 16943775, Free PMC Article
    4. SAFER, an Analysis Method of Quantitative Proteomic Data, Reveals New Interactors of the C. elegans Autophagic Protein LGG-1. Yi Z, et al. J Proteome Res, 2016 May 6. PMID 26999449
    5. The TORC1 phosphoproteome in C. elegans reveals roles in transcription and autophagy. Sewell AK, et al. iScience, 2022 May 20. PMID 35479415, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in peroxisome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Hydroxysteroid dehydrogenase-like protein 2
    NP_001021972.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      5617128..5619319 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001026801.7 → NP_001021972.1  Hydroxysteroid dehydrogenase-like protein 2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001021972.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q09979
      Conserved Domains (2) summary
      PRK08278
      Location:9 → 275
      PRK08278; SDR family oxidoreductase
      pfam02036
      Location:319 → 411
      SCP2; SCP-2 sterol transfer family
    Nucleotide Protein
    Heading Accession and Version

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