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    Y71G12B.27 Cyclin-dependent kinases regulatory subunit [ Caenorhabditis elegans ]

    Gene ID: 171745, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y71G12B.27
    Official Full Name
    Cyclin-dependent kinases regulatory subunit
    Primary source
    WormBase:WBGene00022162
    Locus tag
    CELE_Y71G12B.27
    See related
    AllianceGenome:WB:WBGene00022162
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable several functions, including cyclin-dependent protein serine/threonine kinase activator activity; histone binding activity; and ubiquitin binding activity. Predicted to be involved in regulation of mitotic cell cycle. Predicted to be part of SCF ubiquitin ligase complex and cyclin-dependent protein kinase holoenzyme complex. Orthologous to human CKS2 (CDC28 protein kinase regulatory subunit 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y71G12B.27 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003279.8 (1797435..1798722, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene NAD(P)-bd_dom domain-containing protein;NAD(P)-binding domain-containing protein Neighboring gene Apolipophorin Neighboring gene putative peptidylglycine alpha-hydroxylating monooxygenase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables cyclin-dependent protein serine/threonine kinase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables cyclin-dependent protein serine/threonine kinase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ubiquitin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cyclin-dependent protein kinase holoenzyme complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Cyclin-dependent kinases regulatory subunit
    NP_490896.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      1797435..1798722 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058495.5 → NP_490896.1  Cyclin-dependent kinases regulatory subunit [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_490896.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95XM4
      Conserved Domains (1) summary
      pfam01111
      Location:6 → 71
      CKS; Cyclin-dependent kinase regulatory subunit
    Nucleotide Protein
    Heading Accession and Version

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