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    tmem-258 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TMEM258 [ Caenorhabditis elegans ]

    Gene ID: 179094, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tmem-258
    Official Full Name
    Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TMEM258
    Primary source
    WormBase:WBGene00021960
    Locus tag
    CELE_Y57E12AM.1
    See related
    AllianceGenome:WB:WBGene00021960
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in protein N-linked glycosylation. Predicted to be located in cytoplasm and membrane. Predicted to be part of protein-containing complex. Orthologous to human TMEM258 (transmembrane protein 258). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See tmem-258 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    2
    Sequence:
    Chromosome: V; NC_003283.11 (7063174..7063718)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Serine incorporator 1 Neighboring gene BPTI/Kunitz inhibitor domain-containing protein Neighboring gene tRNA-Glu Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. tmem-258 is dispensable for both nuclear anchorage and migration in C. elegans. Gregory E, et al. MicroPubl Biol, 2020 Jan 2. PMID 32550492, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in protein N-linked glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of oligosaccharyltransferase complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of protein-containing complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TMEM258
    NP_504794.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      7063174..7063718
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_072393.7 → NP_504794.1  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TMEM258 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504794.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q965T1
      Conserved Domains (1) summary
      pfam05251
      Location:7 → 79
      Ost5; Oligosaccharyltransferase subunit 5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q965T1.1

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