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    mam-1 MAM domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 180439, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mam-1
    Official Full Name
    MAM domain-containing protein
    Primary source
    WormBase:WBGene00022504
    Locus tag
    CELE_ZC13.3
    See related
    AllianceGenome:WB:WBGene00022504
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in regulation of T cell activation and regulation of T cell migration. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See mam-1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    14
    Sequence:
    Chromosome: X; NC_003284.9 (882951..888394, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Putative serine protease F56F10.1 Neighboring gene RING-type domain-containing protein Neighboring gene Transmembrane protein Neighboring gene ncRNA Neighboring gene Protein male abnormal 7

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B. Okahata M, et al. Sci Rep, 2024 Mar 5. PMID 38443452, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables transmembrane signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of T cell activation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of T cell migration IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in type II interferon production IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    MAM domain-containing protein
    NP_001355389.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      882951..888394 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001368493.2 → NP_001355389.1  MAM domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95Q40
      Conserved Domains (1) summary
      cl27660
      Location:45 → 191
      MAM; Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members ...
    Nucleotide Protein
    Heading Accession and Version

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