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    gpr-158 G-protein coupled receptors family 3 profile domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 3565054, updated on 2-Nov-2024

    Summary

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    Official Symbol
    gpr-158
    Official Full Name
    G-protein coupled receptors family 3 profile domain-containing protein
    Primary source
    WormBase:WBGene00009558
    Locus tag
    CELE_F39B2.8
    See related
    AllianceGenome:WB:WBGene00009558
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Is expressed in head neurons; motor neurons; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1E. Orthologous to human GPR158 (G protein-coupled receptor 158) and GPR179 (G protein-coupled receptor 179). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See gpr-158 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    9
    Sequence:
    Chromosome: I; NC_003279.8 (14760638..14768989, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Transmembrane protein 107 Neighboring gene ncRNA Neighboring gene Small ribosomal subunit protein eS26 Neighboring gene ncRNA Neighboring gene TrmE-type G domain-containing protein Neighboring gene SH2 domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cell-specific microarray profiling experiments reveal a comprehensive picture of gene expression in the C. elegans nervous system. Von Stetina SE, et al. Genome Biol, 2007. PMID 17612406, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    G-protein coupled receptors family 3 profile domain-containing protein
    NP_493572.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      14760638..14768989 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_061171.7 → NP_493572.2  G-protein coupled receptors family 3 profile domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_493572.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O45500
      Conserved Domains (2) summary
      cd14964
      Location:211 → 233
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:211 → 448
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    Nucleotide Protein
    Heading Accession and Version

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