U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    SOL1 Sol1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855769, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    SOL1
    Official Full Name
    Sol1p
    Primary source
    SGD:S000005317
    Locus tag
    YNR034W
    See related
    AllianceGenome:SGD:S000005317; FungiDB:YNR034W; VEuPathDB:YNR034W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable 6-phosphogluconolactonase activity. Involved in tRNA export from nucleus. Located in nucleus. Orthologous to human PGLS (6-phosphogluconolactonase). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See SOL1 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (690321..691286)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene ubiquitin-like protein HUB1 Neighboring gene 4-amino-4-deoxychorismate synthase Neighboring gene Ego4p Neighboring gene Arc35p

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Los1p, involved in yeast pre-tRNA splicing, positively regulates members of the SOL gene family. Shen WC, et al. Genetics, 1996 Jun. PMID 8725220, Free PMC Article
    2. Division of labor among the yeast Sol proteins implicated in tRNA nuclear export and carbohydrate metabolism. Stanford DR, et al. Genetics, 2004 Sep. PMID 15454531, Free PMC Article
    3. The extensive and condition-dependent nature of epistasis among whole-genome duplicates in yeast. Musso G, et al. Genome Res, 2008 Jul. PMID 18463300, Free PMC Article
    4. Glc7/protein phosphatase 1 regulatory subunits can oppose the Ipl1/aurora protein kinase by redistributing Glc7. Pinsky BA, et al. Mol Cell Biol, 2006 Apr. PMID 16537909, Free PMC Article
    5. Sequestration of mRNAs Modulates the Timing of Translation during Meiosis in Budding Yeast. Jin L, et al. Mol Cell Biol, 2015 Oct. PMID 26217015, Free PMC Article

    See all (39) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables 6-phosphogluconolactonase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in pentose-phosphate shunt IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in pentose-phosphate shunt, oxidative branch IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in tRNA export from nucleus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Sol1p
    NP_014432.3
    • Protein with a possible role in tRNA export; shows similarity to 6-phosphogluconolactonase non-catalytic domains but does not exhibit this enzymatic activity; homologous to Sol3p and Sol4p; SOL1 has a paralog, SOL2, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      690321..691286
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183211.3 → NP_014432.3  TPA: Sol1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014432.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W1K9, P50278
      UniProtKB/TrEMBL
      A6ZSA8, B3LPK9, B5VR63, C7GLM3, C8ZFR2, G2WL91, N1P4S8
      Conserved Domains (1) summary
      cd01400
      Location:92 → 296
      6PGL; 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard against the ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P50278.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools