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    C15H9.4 Transmembrane and coiled-coil domains protein 2 [ Caenorhabditis elegans ]

    Gene ID: 182643, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C15H9.4
    Official Full Name
    Transmembrane and coiled-coil domains protein 2
    Primary source
    WormBase:WBGene00015800
    Locus tag
    CELE_C15H9.4
    See related
    AllianceGenome:WB:WBGene00015800
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in membrane. Predicted to be active in endomembrane system. Orthologous to several human genes including TMCC1 (transmembrane and coiled-coil domain family 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See C15H9.4 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    11
    Sequence:
    Chromosome: X; NC_003284.9 (6097643..6106107)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Heat shock 70 kDa protein C Neighboring gene GOST seven transmembrane domain-containing protein Neighboring gene ncRNA Neighboring gene UPAR/Ly6 domain-containing protein Neighboring gene Kynureninase Neighboring gene Peroxisomal assembly protein PEX3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. F-actin asymmetry and the endoplasmic reticulum-associated TCC-1 protein contribute to stereotypic spindle movements in the Caenorhabditis elegans embryo. Berends CW, et al. Mol Biol Cell, 2013 Jul. PMID 23699393, Free PMC Article
    2. Trifunctional cross-linker for mapping protein-protein interaction networks and comparing protein conformational states. Tan D, et al. Elife, 2016 Mar 8. PMID 26952210, Free PMC Article
    3. A combined binary interaction and phenotypic map of C. elegans cell polarity proteins. Koorman T, et al. Nat Cell Biol, 2016 Mar. PMID 26780296, Free PMC Article
    4. Characterization of the intracellular neurexin interactome by in vivo proximity ligation suggests its involvement in presynaptic actin assembly. Schaan Profes M, et al. PLoS Biol, 2024 Jan. PMID 38252619, Free PMC Article
    5. A protein domain-based interactome network for C. elegans early embryogenesis. Boxem M, et al. Cell, 2008 Aug 8. PMID 18692475, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Transmembrane and coiled-coil domains protein 2
    NP_509021.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      6097643..6106107
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076620.5 → NP_509021.2  Transmembrane and coiled-coil domains protein 2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509021.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q18025
      Conserved Domains (1) summary
      pfam10267
      Location:24 → 445
      Tmemb_cc2; Predicted transmembrane and coiled-coil 2 protein
    Nucleotide Protein
    Heading Accession and Version

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