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    gplb-1 Glycoprotein hormone subunit beta domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 188778, updated on 9-Dec-2024

    Summary

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    Official Symbol
    gplb-1
    Official Full Name
    Glycoprotein hormone subunit beta domain-containing protein
    Primary source
    WormBase:WBGene00020722
    Locus tag
    CELE_T23B12.8
    See related
    AllianceGenome:WB:WBGene00020722
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable hormone activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in extracellular region. Predicted to be active in cytoplasm and extracellular space. Is expressed in GABAergic neurons; head mesodermal cell; and intestinal muscle. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See gplb-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    4
    Sequence:
    Chromosome: V; NC_003283.11 (8470013..8471242, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene 28S ribosomal protein S2, mitochondrial Neighboring gene Large ribosomal subunit protein uL4m Neighboring gene PHD-type domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA-Lys Neighboring gene Peroxidasin homolog pxn-1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Ancestral glycoprotein hormone-receptor pathway controls growth in C. elegans. Kenis S, et al. Front Endocrinol (Lausanne), 2023. PMID 37409228, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables hormone activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Glycoprotein hormone subunit beta domain-containing protein
    NP_001367962.1
    • Confirmed by transcript evidence
    NP_001380019.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      8470013..8471242 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001392563.1 → NP_001380019.1  Glycoprotein hormone subunit beta domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EEJ3
      Conserved Domains (1) summary
      cl21545
      Location:29 → 91
      GHB_like; Glycoprotein hormone beta chain homologues

    2. NM_001380708.2 → NP_001367962.1  Glycoprotein hormone subunit beta domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A7DT38
      Conserved Domains (1) summary
      cl21545
      Location:55 → 117
      GHB_like; Glycoprotein hormone beta chain homologues
    Nucleotide Protein
    Heading Accession and Version

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