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    gmeb-1 SAND domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 182061, updated on 9-Dec-2024

    Summary

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    Official Symbol
    gmeb-1
    Official Full Name
    SAND domain-containing protein
    Primary source
    WormBase:WBGene00015285
    Locus tag
    CELE_C01B12.2
    See related
    AllianceGenome:WB:WBGene00015285
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be located in nucleus. Is expressed in anal region; head neurons; and tail. Orthologous to human GMEB1 (glucocorticoid modulatory element binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See gmeb-1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    5
    Sequence:
    Chromosome: II; NC_003280.10 (19538..22169)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Bestrophin homolog Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The activity of protein phosphatase 5 towards native clients is modulated by the middle- and C-terminal domains of Hsp90. Haslbeck V, et al. Sci Rep, 2015 Nov 23. PMID 26593036, Free PMC Article
    2. A 4D single-cell protein atlas of transcription factors delineates spatiotemporal patterning during embryogenesis. Ma X, et al. Nat Methods, 2021 Aug. PMID 34312566
    3. A transcriptional cofactor regulatory network for the C. elegans intestine. Horowitz BB, et al. G3 (Bethesda), 2023 Jul 5. PMID 37119809, Free PMC Article
    4. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article
    5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The activity of protein phosphatase 5 towards native clients, such as glucocorticoid receptor, is modulated by the middle- and C-terminal domains of Hsp90.
      Title: The activity of protein phosphatase 5 towards native clients is modulated by the middle- and C-terminal domains of Hsp90.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    SAND domain-containing protein
    NP_493634.4
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      19538..22169
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_061233.9 → NP_493634.4  SAND domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_493634.4

      Status: REVIEWED

      UniProtKB/TrEMBL
      O17208
      Conserved Domains (1) summary
      pfam01342
      Location:67 → 143
      SAND; SAND domain
    Nucleotide Protein
    Heading Accession and Version

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