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    sop-3 Mediator complex subunit 1;Mediator of RNA polymerase II transcription subunit 1.1 [ Caenorhabditis elegans ]

    Gene ID: 171840, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sop-3
    Official Full Name
    Mediator complex subunit 1;Mediator of RNA polymerase II transcription subunit 1.1
    Primary source
    WormBase:WBGene00004946
    Locus tag
    CELE_Y71F9B.10
    See related
    AllianceGenome:WB:WBGene00004946
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in nucleus. Is expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P5.p hermaphrodite; P6.p hermaphrodite; and neurons. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See sop-3 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    15
    Sequence:
    Chromosome: I; NC_003279.8 (2761158..2776104, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene L-gulonate 3-dehydrogenase Neighboring gene ncRNA Neighboring gene Transmembrane protein Neighboring gene NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 Neighboring gene Glycoprotein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The novel C. elegans gene sop-3 modulates Wnt signaling to regulate Hox gene expression. Zhang H, et al. Development, 2001 Mar. PMID 11171401
    2. Transcriptional control of cell-cycle quiescence during C. elegans development. Clayton JE, et al. Dev Biol, 2008 Jan 15. PMID 18082681, Free PMC Article
    3. Canonical and non-canonical Wnt signaling pathways in Caenorhabditis elegans: variations on a common signaling theme. Korswagen HC. Bioessays, 2002 Sep. PMID 12210516
    4. An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis. Yang F, et al. Nature, 2006 Aug 10. PMID 16799563
    5. Wnt signaling. Eisenmann DM. WormBook, 2005 Jun 25. PMID 18050402, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Mediator complex subunit 1;Mediator of RNA polymerase II transcription subunit 1.1
    NP_001293373.1
    • Confirmed by transcript evidence
    NP_001293374.1
    • Confirmed by transcript evidence
    NP_001293375.1
    • Confirmed by transcript evidence
    NP_001293376.1
    • Confirmed by transcript evidence
    NP_001364504.1
    • Confirmed by transcript evidence
    NP_001364767.1
    • Confirmed by transcript evidence
    NP_740821.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      2761158..2776104 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001377816.2 → NP_001364504.1  Mediator of RNA polymerase II transcription subunit 1.1 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9MMF7

    2. NM_001306444.3 → NP_001293373.1  Mediator of RNA polymerase II transcription subunit 1.1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293373.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A078BPF6

    3. NM_170837.6 → NP_740821.1  Mediator of RNA polymerase II transcription subunit 1.1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_740821.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q95Y43, Q9GPV1, Q9N4G4

    4. NM_001377813.3 → NP_001364767.1  Mediator of RNA polymerase II transcription subunit 1.1 [Caenorhabditis elegans]

      Status: REVIEWED

    5. NM_001306445.3 → NP_001293374.1  Mediator complex subunit 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293374.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A078BPE0

    6. NM_001306446.3 → NP_001293375.1  Mediator complex subunit 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293375.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A078BQI3

    7. NM_001306447.3 → NP_001293376.1  Mediator of RNA polymerase II transcription subunit 1.1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293376.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A078BTJ0
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9N4G4.2

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