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    • Showing Current items.

    K07A3.3 ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial [ Caenorhabditis elegans ]

    Gene ID: 171817, updated on 9-Dec-2024

    Summary

    Official Symbol
    K07A3.3
    Official Full Name
    ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial
    Primary source
    WormBase:WBGene00019461
    Locus tag
    CELE_K07A3.3
    See related
    AllianceGenome:WB:WBGene00019461
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be active in mitochondrial matrix. Human ortholog(s) of this gene implicated in erythropoietic protoporphyria. Orthologous to human CLPX (caseinolytic mitochondrial matrix peptidase chaperone subunit X). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See K07A3.3 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    9
    Sequence:
    Chromosome: I; NC_003279.8 (2599979..2602650)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene fructose-bisphosphatase Neighboring gene SSD domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Alpha-catulin Neighboring gene ncRNA

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP hydrolysis activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in proteolysis involved in protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in mitochondrial matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial
    NP_001021562.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      2599979..2602650
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001026391.4NP_001021562.1  ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001021562.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q65XY4
      Conserved Domains (3) summary
      smart01086
      Location:413497
      ClpB_D2-small; C-terminal, D2-small domain, of ClpB protein
      COG1220
      Location:99510
      HslU; ATP-dependent protease HslVU (ClpYQ), ATPase subunit [Posttranslational modification, protein turnover, chaperones]
      pfam07724
      Location:194406
      AAA_2; AAA domain (Cdc48 subfamily)

    RNA

    1. NR_131362.1 RNA Sequence

      Status: REVIEWED