R07B7.8 Lipase_GDSL domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: R07B7.8
Official Full Name: Lipase_GDSL domain-containing protein
Primary source: WormBase:WBGene00011092
Locus tag: CELE_R07B7.8
See related: AllianceGenome:WB:WBGene00011092
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable phospholipase activity. Predicted to be involved in phospholipid metabolic process. Predicted to be located in membrane. Orthologous to human PLB1 (phospholipase B1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See R07B7.8 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 12

Sequence:: Chromosome: V; NC_003283.11 (12081085..12084316, complement)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

R07B7.8 (e-PCR)
- UniSTS:314756

R07B7.10 (e-PCR)
- UniSTS:314757

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables hydrolase activity, acting on ester bonds	IEA Inferred from Electronic Annotation more info
enables phospholipase activity	IBA Inferred from Biological aspect of Ancestor more info
enables phospholipase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in phospholipid metabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Lipase_GDSL domain-containing protein

NP_506029.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

12081085..12084316 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_073628.6 → NP_506029.2 Lipase_GDSL domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_506029.2

Status: REVIEWED

UniProtKB/TrEMBL

Q21799

Conserved Domains (1) summary

cl01053
Location:123 → 403

SGNH_hydrolase; or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical ...