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    cyp-33C8 CYtochrome P450 family [ Caenorhabditis elegans ]

    Gene ID: 187705, updated on 27-Dec-2024

    Summary

    Official Symbol
    cyp-33C8
    Official Full Name
    CYtochrome P450 family
    Primary source
    WormBase:WBGene00019967
    Locus tag
    CELE_R08F11.3
    See related
    AllianceGenome:WB:WBGene00019967
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable heme binding activity and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in end stage renal disease and renal hypertension. Orthologous to human CYP2C8 (cytochrome P450 family 2 subfamily C member 8). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See cyp-33C8 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    4
    Sequence:
    Chromosome: V; NC_003283.11 (3800782..3803542, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Peroxidase Neighboring gene pseudo Neighboring gene Serpentine Receptor, class T Neighboring gene Methyltransferase domain-containing protein Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in organic acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in xenobiotic metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    CYtochrome P450 family
    NP_504051.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      3800782..3803542 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_071650.7NP_504051.1  CYtochrome P450 family [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504051.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O02641
      Conserved Domains (1) summary
      pfam00067
      Location:37484
      p450; Cytochrome P450