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    msi-1 RNA-binding protein Musashi homolog 1 [ Caenorhabditis elegans ]

    Gene ID: 175514, updated on 9-Dec-2024

    Summary

    Official Symbol
    msi-1
    Official Full Name
    RNA-binding protein Musashi homolog 1
    Primary source
    WormBase:WBGene00003423
    Locus tag
    CELE_R10E9.1
    See related
    AllianceGenome:WB:WBGene00003423
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables mRNA binding activity. Involved in nervous system process. Located in cytoplasm. Is expressed in SMDVL; head neurons; and intestine. Orthologous to human MSI1 (musashi RNA binding protein 1) and MSI2 (musashi RNA binding protein 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See msi-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    8
    Sequence:
    Chromosome: III; NC_003281.10 (3964660..3976391, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein;MARVEL domain-containing protein Neighboring gene Major sperm protein Neighboring gene Uncharacterized protein Neighboring gene LIM zinc-binding domain-containing protein Neighboring gene Uncharacterized protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables mRNA binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in nervous system process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of translation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in perikaryon IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    RNA-binding protein Musashi homolog 1
    NP_001369851.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      3964660..3976391 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001384060.2NP_001369851.1  RNA-binding protein Musashi homolog 1 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      G5EFS2
      Conserved Domains (2) summary
      cd12323
      Location:135208
      RRM2_MSI; RNA recognition motif 2 (RRM2) found in RNA-binding protein Musashi homologs Musashi-1, Musashi-2 and similar proteins
      cd12576
      Location:46121
      RRM1_MSI; RNA recognition motif 1 (RRM1) found in RNA-binding protein Musashi homolog Musashi-1, Musashi-2 and similar proteins