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    W03G11.3 Putative alpha-L-fucosidase [ Caenorhabditis elegans ]

    Gene ID: 189173, updated on 9-Dec-2024

    Summary

    Official Symbol
    W03G11.3
    Official Full Name
    Putative alpha-L-fucosidase
    Primary source
    WormBase:WBGene00012225
    Locus tag
    CELE_W03G11.3
    See related
    AllianceGenome:WB:WBGene00012225
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable alpha-L-fucosidase activity. Predicted to be involved in fucose metabolic process and glycoside catabolic process. Predicted to be active in lysosome. Human ortholog(s) of this gene implicated in fucosidosis. Orthologous to human FUCA1 (alpha-L-fucosidase 1) and FUCA2 (alpha-L-fucosidase 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See W03G11.3 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    11
    Sequence:
    Chromosome: X; NC_003284.9 (12100191..12103812, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein Neighboring gene tRNA-Lys

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables alpha-L-fucosidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables alpha-L-fucosidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables fucosidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity, acting on glycosyl bonds IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in fucose metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in fucose metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in glycoside catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in lysosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Putative alpha-L-fucosidase
    NP_510020.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      12100191..12103812 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_077619.6NP_510020.2  Putative alpha-L-fucosidase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_510020.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P49713
      Conserved Domains (2) summary
      smart00812
      Location:12377
      Alpha_L_fucos; Alpha-L-fucosidase
      COG3669
      Location:44355
      AfuC; Alpha-L-fucosidase [Carbohydrate transport and metabolism]