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    unc-7 Innexin;Innexin unc-7 [ Caenorhabditis elegans ]

    Gene ID: 181608, updated on 2-Nov-2024

    Summary

    Official Symbol
    unc-7
    Official Full Name
    Innexin;Innexin unc-7
    Primary source
    WormBase:WBGene00006747
    Locus tag
    CELE_R07D5.1
    See related
    AllianceGenome:WB:WBGene00006747
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables gap junction channel activity. Involved in several processes, including egg-laying behavior; response to anesthetic; and spicule insertion. Located in gap junction and neuron projection membrane. Is expressed in several structures, including intestine; muscle cell; nervous system; and pharyngeal gland cell. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See unc-7 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    15
    Sequence:
    Chromosome: X; NC_003284.9 (15120846..15147740, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA-Arg Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables gap junction channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables gap junction channel activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables gap junction channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables gap junction hemi-channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in cell-cell junction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in gap junction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in gap junction IEA
    Inferred from Electronic Annotation
    more info
     
    located_in gap junction IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in neuron projection membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Innexin;Innexin unc-7
    NP_001257255.1
    • Confirmed by transcript evidence
    NP_001257256.1
    • Partially confirmed by transcript evidence
    NP_001337312.1
    • Partially confirmed by transcript evidence
    NP_001337313.1
    • Partially confirmed by transcript evidence
    NP_001337316.1
    • Partially confirmed by transcript evidence
    NP_001337317.1
    • Partially confirmed by transcript evidence
    NP_001337318.1
    • Confirmed by transcript evidence
    NP_001337319.1
    • Confirmed by transcript evidence
    NP_001337320.1
    • Confirmed by transcript evidence
    NP_001379507.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      15120846..15147740 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001350356.3NP_001337319.1  Innexin [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1T5HUM7
      Conserved Domains (1) summary
      pfam00876
      Location:93453
      Innexin
    2. NM_001270326.3NP_001257255.1  Innexin unc-7 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001257255.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q03412
      Conserved Domains (1) summary
      pfam00876
      Location:139501
      Innexin; Innexin
    3. NM_001350352.4NP_001337313.1  Innexin [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1T5HUM1
      Conserved Domains (1) summary
      pfam00876
      Location:163523
      Innexin
    4. NM_001350354.3NP_001337317.1  Innexin [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1T5HUM6
      Conserved Domains (1) summary
      pfam00876
      Location:80440
      Innexin
    5. NM_001392896.1NP_001379507.1  Innexin [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      C8JQR8
      Conserved Domains (1) summary
      pfam00876
      Location:20380
      Innexin
    6. NM_001350353.4NP_001337312.1  Innexin [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1T5HUM5
      Conserved Domains (1) summary
      pfam00876
      Location:163525
      Innexin
    7. NM_001350355.3NP_001337316.1  Innexin [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1T5HUM3
      Conserved Domains (1) summary
      pfam00876
      Location:80442
      Innexin
    8. NM_001350357.3NP_001337318.1  Innexin [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1T5HUM9
      Conserved Domains (1) summary
      pfam00876
      Location:93455
      Innexin
    9. NM_001350358.3NP_001337320.1  Innexin [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1T5HUN4
      Conserved Domains (1) summary
      pfam00876
      Location:139499
      Innexin
    10. NM_001270327.3NP_001257256.1  Innexin [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001257256.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C8JQR7
      Conserved Domains (1) summary
      pfam00876
      Location:71433
      Innexin; Innexin