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    F10E7.9 Amino acid permease/ SLC12A domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 174167, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F10E7.9
    Official Full Name
    Amino acid permease/ SLC12A domain-containing protein
    Primary source
    WormBase:WBGene00017350
    Locus tag
    CELE_F10E7.9
    See related
    AllianceGenome:WB:WBGene00017350
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable potassium:chloride symporter activity. Predicted to be involved in several processes, including chloride ion homeostasis; monoatomic ion transmembrane transport; and potassium ion homeostasis. Predicted to be located in membrane. Is expressed in nerve ring; retrovesicular ganglion neurons; and tail neurons. Orthologous to human SLC12A8 (solute carrier family 12 member 8). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F10E7.9 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    7
    Sequence:
    Chromosome: II; NC_003280.10 (7106412..7110056, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene DUF3402 domain-containing protein;Far11/STRP C-terminal domain-containing protein Neighboring gene Large ribosomal subunit protein eL33 Neighboring gene Ribosome assembly factor mrt4 Neighboring gene Uncharacterized protein Neighboring gene ZP domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables chloride:monoatomic cation symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables potassium:chloride symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell volume homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in chloride ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in chloride transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in potassium ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in potassium ion import across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Amino acid permease/ SLC12A domain-containing protein
    NP_495469.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      7106412..7110056 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063068.8 → NP_495469.2  Amino acid permease/ SLC12A domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495469.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19301
      Conserved Domains (1) summary
      TIGR00930
      Location:47 → 557
      2a30; K-Cl cotransporter
    Nucleotide Protein
    Heading Accession and Version

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