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    Smim3 small integral membrane protein 3 [ Mus musculus (house mouse) ]

    Gene ID: 106878, updated on 27-Nov-2024

    Summary

    Official Symbol
    Smim3provided by MGI
    Official Full Name
    small integral membrane protein 3provided by MGI
    Primary source
    MGI:MGI:1917088
    See related
    Ensembl:ENSMUSG00000038059 AllianceGenome:MGI:1917088
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Nid67; cI-41; 2010002N04Rik
    Summary
    Predicted to enable identical protein binding activity. Predicted to be located in membrane. Is expressed in liver left lobe; liver right lobe; and thyroid gland. Orthologous to human SMIM3 (small integral membrane protein 3). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in ovary adult (RPKM 8.4), lung adult (RPKM 8.1) and 26 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Smim3 in Genome Data Viewer
    Location:
    18 D3; 18 34.36 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (60607263..60635055, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (60474191..60518949, complement)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene predicted pseudogene 6960 Neighboring gene interferon-inducible GTPase-like pseudogene Neighboring gene STARR-positive B cell enhancer mm9_chr18:60622203-60622504 Neighboring gene STARR-seq mESC enhancer starr_44715 Neighboring gene predicted gene, 46628 Neighboring gene dynactin 4 Neighboring gene predicted gene, 52358

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Gene trapped (1) 
    • Targeted (1)  1 citation

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables identical protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    small integral membrane protein 3
    Names
    NGF-induced differentiation clone 67 protein
    putative small membrane protein NID67
    small membrane protein NID67

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_134133.2NP_598894.1  small integral membrane protein 3

      See identical proteins and their annotated locations for NP_598894.1

      Status: VALIDATED

      Source sequence(s)
      AF313412, AK143383, AK155873
      Consensus CDS
      CCDS37831.1
      UniProtKB/Swiss-Prot
      Q921E9, Q99PE5
      UniProtKB/TrEMBL
      Q3TAJ2, Q3U1M0
      Related
      ENSMUSP00000039285.7, ENSMUST00000042710.8
      Conserved Domains (1) summary
      pfam17307
      Location:160
      Smim3; Small integral membrane protein 3

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      60607263..60635055 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011246797.3XP_011245099.1  small integral membrane protein 3 isoform X2

      See identical proteins and their annotated locations for XP_011245099.1

      UniProtKB/Swiss-Prot
      Q921E9, Q99PE5
      UniProtKB/TrEMBL
      Q3TAJ2, Q3U1M0
      Conserved Domains (1) summary
      pfam17307
      Location:160
      Smim3; Small integral membrane protein 3
    2. XM_006525481.5XP_006525544.2  small integral membrane protein 3 isoform X1