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    CAF120 Caf120p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855443, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CAF120
    Official Full Name
    Caf120p
    Primary source
    SGD:S000005222
    Locus tag
    YNL278W
    See related
    AllianceGenome:SGD:S000005222; FungiDB:YNL278W; VEuPathDB:YNL278W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable protein kinase activity. Predicted to be involved in signal transduction. Located in cellular bud neck. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See CAF120 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (113271..116453)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene delta(14)-sterol reductase Neighboring gene pheromone-regulated protein PRM1 Neighboring gene uncharacterized protein Neighboring gene homoserine O-acetyltransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dual Repressive Function by Cip1, a Budding Yeast Analog of p21, in Cell-Cycle START Regulation. Li P, et al. Front Microbiol, 2020. PMID 32733430, Free PMC Article
    2. Laboratory evolution of new lactate transporter genes in a jen1Δ mutant of Saccharomyces cerevisiae and their identification as ADY2 alleles by whole-genome resequencing and transcriptome analysis. de Kok S, et al. FEMS Yeast Res, 2012 May. PMID 22257278
    3. Proteome-wide remodeling of protein location and function by stress. Lee K, et al. Proc Natl Acad Sci U S A, 2014 Jul 29. PMID 25028499, Free PMC Article
    4. Purification and characterization of the 1.0 MDa CCR4-NOT complex identifies two novel components of the complex. Chen J, et al. J Mol Biol, 2001 Dec 7. PMID 11733989
    5. Using HHsearch to tackle proteins of unknown function: A pilot study with PH domains. Fidler DR, et al. Traffic, 2016 Nov. PMID 27601190, Free PMC Article

    See all (40) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables protein kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cellular bud neck IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cellular bud neck IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Caf120p
    NP_014121.1
    • Part of the CCR4-NOT transcriptional regulatory complex; involved in controlling mRNA initiation, elongation, and degradation; contains a PH-like domain; CAF120 has a paralog, SKG3, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      113271..116453
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183116.1 → NP_014121.1  TPA: Caf120p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014121.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W0R6, P53836
      UniProtKB/TrEMBL
      C7GP86, N1P4Y8
      Conserved Domains (2) summary
      PHA03247
      Location:808 → 1039
      PHA03247; large tegument protein UL36; Provisional
      pfam00169
      Location:88 → 204
      PH; PH domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53836.1

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