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    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852737, updated on 9-Dec-2024

    Summary

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    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000003108
    Locus tag
    YGL140C
    See related
    AllianceGenome:SGD:S000003108; FungiDB:YGL140C; VEuPathDB:YGL140C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (241353..245012, complement)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene putative glycosylphosphatidylinositol-alpha 1,2 mannosyltransferase Neighboring gene ubiquitin-ubiquitin ligase HUL5 Neighboring gene putative flavin adenine dinucleotide transporter Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001139.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The sequence of a nearly unclonable 22.8 kb segment on the left arm chromosome VII from Saccharomyces cerevisiae reveals ARO2, RPL9A, TIP1, MRF1 genes and six new open reading frames. Voet M, et al. Yeast, 1997 Feb. PMID 9046099
    2. Disruption of 12 ORFs located on chromosomes IV, VII and XIV of Saccharomyces cerevisiae reveals two essential genes. Volckaert G, et al. Yeast, 2003 Jan 15. PMID 12489128
    3. Noncanonical regulation of phosphatidylserine metabolism by a Sec14-like protein and a lipid kinase. Wang Y, et al. J Cell Biol, 2020 May 4. PMID 32303746, Free PMC Article
    4. The GET pathway is a major bottleneck for maintaining proteostasis in Saccharomyces cerevisiae. Josefson R, et al. Sci Rep, 2023 Jun 7. PMID 37286562, Free PMC Article
    5. Functional profiling of the Saccharomyces cerevisiae genome. Giaever G, et al. Nature, 2002 Jul 25. PMID 12140549

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_011375.1
    • hypothetical protein; non-essential gene; contains multiple predicted transmembrane domains

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      241353..245012 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181005.1 → NP_011375.1  TPA: uncharacterized protein YGL140C [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011375.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VU09, P53120
      UniProtKB/TrEMBL
      A6ZU43, N1P3D2
      Conserved Domains (2) summary
      pfam10337
      Location:9 → 438
      ArAE_2_N; Putative ER transporter, 6TM, N-terminal
      pfam13515
      Location:654 → 780
      FUSC_2; Fusaric acid resistance protein-like
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53120.1

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