U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Cetn1 centrin 1 [ Mus musculus (house mouse) ]

    Gene ID: 26369, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cetn1provided by MGI
    Official Full Name
    centrin 1provided by MGI
    Primary source
    MGI:MGI:1347086
    See related
    Ensembl:ENSMUSG00000050996 AllianceGenome:MGI:1347086
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    caltractin
    Summary
    Enables G-protein beta/gamma-subunit complex binding activity; heterotrimeric G-protein binding activity; and microtubule binding activity. Acts upstream of or within cellular response to heat. Located in centrosome and photoreceptor connecting cilium. Is expressed in embryo; inner cell mass; and photoreceptor layer. Orthologous to human CETN1 (centrin 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Cetn1 in Genome Data Viewer
    Location:
    18 A1; 18 4.91 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (9618419..9619469, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (9618419..9619469, complement)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 31 pseudogene Neighboring gene STARR-seq mESC enhancer starr_43779 Neighboring gene STARR-seq mESC enhancer starr_43780 Neighboring gene predicted gene, 46616 Neighboring gene STARR-seq mESC enhancer starr_43781 Neighboring gene kinectin 1 pseudogene Neighboring gene 60S ribosomal protein L24-like Neighboring gene collectin sub-family member 12

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G-protein beta/gamma-subunit complex binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables heterotrimeric G-protein binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables microtubule binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cellular response to heat IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in centriole replication IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in centriole IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in centriole ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in centrosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in cilium TAS
    Traceable Author Statement
    more info
     
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in microtubule organizing center IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in photoreceptor connecting cilium IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in spindle pole IEA
    Inferred from Electronic Annotation
    more info
     
    located_in spindle pole ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    centrin-1
    Names
    testis-specific murine centrin

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007593.5NP_031619.3  centrin-1

      See identical proteins and their annotated locations for NP_031619.3

      Status: VALIDATED

      Source sequence(s)
      AK006940, AK015808
      Consensus CDS
      CCDS37731.1
      UniProtKB/Swiss-Prot
      P41209, Q3V119, Q9D9G9, Q9DAL6
      Related
      ENSMUSP00000157153.2, ENSMUST00000234003.2
      Conserved Domains (1) summary
      PTZ00183
      Location:15172
      PTZ00183; centrin; Provisional

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      9618419..9619469 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)