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    RPS7B ribosomal 40S subunit protein S7B [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855628, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RPS7B
    Official Full Name
    ribosomal 40S subunit protein S7B
    Primary source
    SGD:S000005040
    Locus tag
    YNL096C
    See related
    AllianceGenome:SGD:S000005040; FungiDB:YNL096C; VEuPathDB:YNL096C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to be a structural constituent of ribosome. Involved in ribosome biogenesis. Part of small-subunit processome. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 8. Orthologous to human RPS7 (ribosomal protein S7). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See RPS7B in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    2
    Sequence:
    Chromosome: XIV; NC_001146.8 (443398..444315, complement)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Pho23p Neighboring gene tRNA-Leu Neighboring gene uncharacterized protein Neighboring gene phosphatidate phosphatase APP1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The yeast ribosomal protein S7 and its genes. Synetos D, et al. J Biol Chem, 1992 Feb 15. PMID 1737755
    2. Association of ribosomal proteins with nascent transcripts in S. cerevisiae. Schroder PA, et al. RNA, 2005 Oct. PMID 16199762, Free PMC Article
    3. Presence of Not5 and ubiquitinated Rps7A in polysome fractions depends upon the Not4 E3 ligase. Panasenko OO, et al. Mol Microbiol, 2012 Feb. PMID 22243599
    4. K29-linked free polyubiquitin chains affect ribosome biogenesis and direct ribosomal proteins to the intranuclear quality control compartment. Garadi Suresh H, et al. Mol Cell, 2024 Jun 20. PMID 38870935,
    5. Farnesol inhibits translation to limit growth and filamentation in C. albicans and S. cerevisiae. Egbe NE, et al. Microb Cell, 2017 Sep 4. PMID 28913344, Free PMC Article

    See all (91) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic translation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in rRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ribosomal small subunit biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ribosome biogenesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic small ribosomal subunit NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of small-subunit processome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ribosomal 40S subunit protein S7B
    NP_014303.3
    • Protein component of the small (40S) ribosomal subunit; interacts with Kti11p; deletion causes hypersensitivity to zymocin; homologous to mammalian ribosomal protein S7, no bacterial homolog; RPS7B has a paralog, RPS7A, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      443398..444315 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182934.3 → NP_014303.3  TPA: ribosomal 40S subunit protein S7B [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014303.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W184, P48164
      UniProtKB/TrEMBL
      A6ZRY5, B3LNV4, C7GUP5, C8ZGD5, E9P9B7, G2WM09, N1P4E6
      Conserved Domains (1) summary
      pfam01251
      Location:7 → 186
      Ribosomal_S7e; Ribosomal protein S7e
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P48164.1

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