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    Cdip1 cell death inducing Trp53 target 1 [ Mus musculus (house mouse) ]

    Gene ID: 66626, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cdip1provided by MGI
    Official Full Name
    cell death inducing Trp53 target 1provided by MGI
    Primary source
    MGI:MGI:1913876
    See related
    Ensembl:ENSMUSG00000004071 AllianceGenome:MGI:1913876
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CDIP; 2700048O17Rik; 5730403B10Rik
    Summary
    Predicted to enable zinc ion binding activity. Predicted to be involved in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. Predicted to act upstream of or within apoptotic process and tumor necrosis factor-mediated signaling pathway. Predicted to be active in cytoplasmic side of late endosome membrane; cytoplasmic side of lysosomal membrane; and nucleus. Is expressed in embryo; otic pit; and otocyst. Orthologous to human CDIP1 (cell death inducing p53 target 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 59.3), testis adult (RPKM 47.9) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Cdip1 in Genome Data Viewer
    Location:
    16 A1; 16 2.47 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (4583325..4608156, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (4765461..4790292, complement)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene DnaJ heat shock protein family (Hsp40) member A3 Neighboring gene STARR-seq mESC enhancer starr_39942 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:4726231-4726340 Neighboring gene NmrA-like family domain containing 1 Neighboring gene heme oxygenase 2 Neighboring gene STARR-seq mESC enhancer starr_39943 Neighboring gene STARR-positive B cell enhancer ABC_E7425 Neighboring gene STARR-seq mESC enhancer starr_39945 Neighboring gene RIKEN cDNA 4930562C15 gene Neighboring gene predicted gene, 36513 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:4878205-4878392 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:4879753-4879936 Neighboring gene UBA-like domain containing 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (2) 
    • Targeted (2) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasmic side of late endosome membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasmic side of late endosome membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasmic side of late endosome membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in cytoplasmic side of lysosomal membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasmic side of lysosomal membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasmic side of lysosomal membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    cell death-inducing p53-target protein 1
    Names
    LITAF-like protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001358078.1NP_001345007.1  cell death-inducing p53-target protein 1 isoform 4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR and has multiple differences in the coding region, but maintains the reading frame, compared to variant 1. This variant encodes isoform 4, which is shorter than isoform 1.
      Source sequence(s)
      AC166903
      Consensus CDS
      CCDS27925.1
      UniProtKB/Swiss-Prot
      Q3UD73, Q9CYP1, Q9DB75
      Conserved Domains (1) summary
      pfam10601
      Location:137205
      zf-LITAF-like; LITAF-like zinc ribbon domain
    2. NM_001358079.2NP_001345008.1  cell death-inducing p53-target protein 1 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AC166903
      Conserved Domains (1) summary
      pfam10601
      Location:158224
      zf-LITAF-like; LITAF-like zinc ribbon domain
    3. NM_001358080.2NP_001345009.1  cell death-inducing p53-target protein 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC166903
      Conserved Domains (1) summary
      pfam10601
      Location:102168
      zf-LITAF-like; LITAF-like zinc ribbon domain
    4. NM_001358081.2NP_001345010.1  cell death-inducing p53-target protein 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC166903
      Consensus CDS
      CCDS88867.1
      Related
      ENSMUSP00000113618.2, ENSMUST00000117713.8
      Conserved Domains (1) summary
      pfam10601
      Location:120186
      zf-LITAF-like; LITAF-like zinc ribbon domain
    5. NM_001358082.2NP_001345011.1  cell death-inducing p53-target protein 1 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC166903
      Consensus CDS
      CCDS27925.1
      UniProtKB/Swiss-Prot
      Q3UD73, Q9CYP1, Q9DB75
      Related
      ENSMUSP00000113889.2, ENSMUST00000118703.8
      Conserved Domains (1) summary
      pfam10601
      Location:137205
      zf-LITAF-like; LITAF-like zinc ribbon domain
    6. NM_025670.5NP_079946.2  cell death-inducing p53-target protein 1 isoform 4

      See identical proteins and their annotated locations for NP_079946.2

      Status: VALIDATED

      Source sequence(s)
      AC166903
      Consensus CDS
      CCDS27925.1
      UniProtKB/Swiss-Prot
      Q3UD73, Q9CYP1, Q9DB75
      Related
      ENSMUSP00000004173.6, ENSMUST00000004173.12
      Conserved Domains (1) summary
      pfam10601
      Location:137205
      zf-LITAF-like; LITAF-like zinc ribbon domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      4583325..4608156 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030249239.1XP_030105099.1  cell death-inducing p53-target protein 1 isoform X1

      UniProtKB/Swiss-Prot
      Q3UD73, Q9CYP1, Q9DB75
      Conserved Domains (1) summary
      pfam10601
      Location:137205
      zf-LITAF-like; LITAF-like zinc ribbon domain
    2. XM_030249240.1XP_030105100.1  cell death-inducing p53-target protein 1 isoform X1

      UniProtKB/Swiss-Prot
      Q3UD73, Q9CYP1, Q9DB75
      Conserved Domains (1) summary
      pfam10601
      Location:137205
      zf-LITAF-like; LITAF-like zinc ribbon domain
    3. XM_006522468.1XP_006522531.1  cell death-inducing p53-target protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006522531.1

      UniProtKB/Swiss-Prot
      Q3UD73, Q9CYP1, Q9DB75
      Conserved Domains (1) summary
      pfam10601
      Location:137205
      zf-LITAF-like; LITAF-like zinc ribbon domain