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    Clec11a C-type lectin domain family 11, member a [ Mus musculus (house mouse) ]

    Gene ID: 20256, updated on 9-Dec-2024

    Summary

    Official Symbol
    Clec11aprovided by MGI
    Official Full Name
    C-type lectin domain family 11, member aprovided by MGI
    Primary source
    MGI:MGI:1298219
    See related
    Ensembl:ENSMUSG00000004473 AllianceGenome:MGI:1298219
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Scgf; Clecsf3
    Summary
    Predicted to enable growth factor activity. Predicted to be involved in ossification and positive regulation of cell population proliferation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; head mesenchyme; renal vasculature; and retina nuclear layer. Orthologous to human CLEC11A (C-type lectin domain containing 11A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in ovary adult (RPKM 13.9), limb E14.5 (RPKM 11.9) and 26 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Clec11a in Genome Data Viewer
    Location:
    7 B3; 7 28.83 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (43953190..43956383, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (44303766..44306959, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene formyl peptide receptor 3 pseudogene Neighboring gene predicted gene 7238 Neighboring gene STARR-positive B cell enhancer ABC_E129 Neighboring gene SH3 and multiple ankyrin repeat domains 1 Neighboring gene RIKEN cDNA 1700008O03 gene Neighboring gene STARR-seq mESC enhancer starr_18792 Neighboring gene predicted gene, 39001

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables carbohydrate binding NAS
    Non-traceable Author Statement
    more info
    PubMed 
    enables growth factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables growth factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables growth factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in ossification IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ossification IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of cell population proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of cell population proliferation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in extracellular region ISO
    Inferred from Sequence Orthology
    more info
     
    located_in extracellular region ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    C-type lectin domain family 11 member A
    Names
    lymphocyte secreted C-type lectin
    osteolectin
    stem cell growth factor

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009131.3NP_033157.1  C-type lectin domain family 11 member A precursor

      See identical proteins and their annotated locations for NP_033157.1

      Status: VALIDATED

      Source sequence(s)
      AC152939, AK042963, BB850120, BE860221, BY115987, BY137682, CD741904
      Consensus CDS
      CCDS21203.1
      UniProtKB/Swiss-Prot
      O88200, Q8C946, Q9CTF0
      Related
      ENSMUSP00000004587.10, ENSMUST00000004587.11
      Conserved Domains (1) summary
      cl02432
      Location:182326
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      43953190..43956383 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)