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    Cnot9 CCR4-NOT transcription complex, subunit 9 [ Mus musculus (house mouse) ]

    Gene ID: 58184, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cnot9provided by MGI
    Official Full Name
    CCR4-NOT transcription complex, subunit 9provided by MGI
    Primary source
    MGI:MGI:1928902
    See related
    Ensembl:ENSMUSG00000026174 AllianceGenome:MGI:1928902
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fl10; Rqcd1; 2610007F23Rik
    Summary
    Predicted to enable several functions, including epidermal growth factor receptor binding activity; nuclear receptor coactivator activity; and protein homodimerization activity. Acts upstream of or within cytokine-mediated signaling pathway. Located in P-body. Is expressed in several structures, including alimentary system; brain; branchial arch; genitourinary system; and sensory organ. Orthologous to human CNOT9 (CCR4-NOT transcription complex subunit 9). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 22.1), limb E14.5 (RPKM 19.1) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Cnot9 in Genome Data Viewer
    Location:
    1 C4; 1 38.54 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (74545192..74570001)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (74506036..74530842)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_01337 Neighboring gene predicted gene, 53562 Neighboring gene CTD small phosphatase 1 Neighboring gene microRNA 26b Neighboring gene villin 1 Neighboring gene ubiquitin specific peptidase 37 Neighboring gene STARR-positive B cell enhancer mm9_chr1:74552349-74552650 Neighboring gene phospholipase C, delta 4 Neighboring gene STARR-seq mESC enhancer starr_01339 Neighboring gene zinc finger protein 142 Neighboring gene STARR-positive B cell enhancer ABC_E791

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables epidermal growth factor receptor binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables epidermal growth factor receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables kinase binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables nuclear receptor coactivator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein domain specific binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein homodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of CCR4-NOT complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of CCR4-NOT complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of CCR4-NOT core complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in P-body IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in P-body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    CCR4-NOT transcription complex subunit 9
    Names
    EPO-induced protein FL10
    RCD1 required for cell differentiation 1 homolog
    cell differentiation protein RCD1 homolog
    cell differentiation protein RQCD1 homolog
    rcd-1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_021383.5NP_067358.1  CCR4-NOT transcription complex subunit 9

      See identical proteins and their annotated locations for NP_067358.1

      Status: VALIDATED

      Source sequence(s)
      BC050898, BC051948, BY705231
      Consensus CDS
      CCDS35615.1
      UniProtKB/Swiss-Prot
      Q9JKY0
      Related
      ENSMUSP00000084466.6, ENSMUST00000087215.7
      Conserved Domains (1) summary
      pfam04078
      Location:25283
      Rcd1; Cell differentiation family, Rcd1-like

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      74545192..74570001
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006496171.4XP_006496234.1  CCR4-NOT transcription complex subunit 9 isoform X1

      See identical proteins and their annotated locations for XP_006496234.1

      Conserved Domains (1) summary
      pfam04078
      Location:1229
      Rcd1; Cell differentiation family, Rcd1-like