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    Akain1 A kinase anchor inhibitor 1 [ Mus musculus (house mouse) ]

    Gene ID: 320722, updated on 27-Nov-2024

    Summary

    Official Symbol
    Akain1provided by MGI
    Official Full Name
    A kinase anchor inhibitor 1provided by MGI
    Primary source
    MGI:MGI:2444600
    See related
    Ensembl:ENSMUSG00000091636 AllianceGenome:MGI:2444600
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    A330050F15Rik
    Summary
    Enables protein kinase A binding activity. Acts upstream of or within negative regulation of protein-containing complex assembly. Located in cytosol. Orthologous to human AKAIN1 (A-kinase anchor inhibitor 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in cerebellum adult (RPKM 4.9), frontal lobe adult (RPKM 1.7) and 1 other tissue See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Akain1 in Genome Data Viewer
    Location:
    17 E1.3; 17 40.46 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (69744906..69796228)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (69437911..69489233)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene zinc finger and BTB domain containing 14 Neighboring gene RIKEN cDNA C030034I22 gene Neighboring gene STARR-seq mESC enhancer starr_43127 Neighboring gene RIKEN cDNA A730049N16 gene Neighboring gene heat shock protein 90, alpha (cytosolic), class A member 1 pseudogene Neighboring gene NSA2 ribosome biogenesis homolog pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein kinase A binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein kinase A binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein kinase A binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of protein-containing complex assembly IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in protein localization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein localization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of protein-containing complex assembly IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    A-kinase anchor protein inhibitor 1
    Names
    A kinase (PRKA) anchor inhibitor 1
    A-kinase anchor protein C18orf42 homolg

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001145192.1NP_001138664.1  A-kinase anchor protein inhibitor 1

      See identical proteins and their annotated locations for NP_001138664.1

      Status: VALIDATED

      Source sequence(s)
      AC127693, AK039494, BB868684
      Consensus CDS
      CCDS50171.1
      UniProtKB/Swiss-Prot
      G3UWD5
      Related
      ENSMUSP00000131134.2, ENSMUST00000169935.2

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      69744906..69796228
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006524415.4XP_006524478.1  A-kinase anchor protein inhibitor 1 isoform X1