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    ddpA putative D,D-dipeptide ABC transporter periplasmic binding protein [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946052, updated on 3-Dec-2024

    Summary

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    Official Symbol
    ddpA
    Official Full Name
    putative D,D-dipeptide ABC transporter periplasmic binding protein
    Primary source
    ECOCYC:G6781
    Locus tag
    b1487
    See related
    ASAP:ABE-0004958
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1481; yddS
    Summary
    First 25 aa are predicted to be a type I signal peptide. [More information is available at EcoGene: EG13790]. YddS is the periplasmic binding component of a predicted peptide ABC transporter. [More information is available at EcoCyc: G6781].
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    Genomic context

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    Sequence:
    NC_000913.3 (1560931..1562481, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative D,D-dipeptide ABC transporter ATP-binding subunit DdpF Neighboring gene putative D,D-dipeptide ABC transporter ATP-binding subunit DdpD Neighboring gene putative D,D-dipeptide ABC transporter membrane subunit DdpC Neighboring gene putative D,D-dipeptide ABC transporter membrane subunit DdpB Neighboring gene D-alanyl-D-alanine dipeptidase Neighboring gene oxygen-sensing c-di-GMP phosphodiesterase DosP

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sulfur and nitrogen limitation in Escherichia coli K-12: specific homeostatic responses. Gyaneshwar P, et al. J Bacteriol, 2005 Feb. PMID 15659685, Free PMC Article
    2. VanX, a bacterial D-alanyl-D-alanine dipeptidase: resistance, immunity, or survival function? Lessard IA, et al. Proc Natl Acad Sci U S A, 1999 Sep 28. PMID 10500118, Free PMC Article
    3. Homologs of the vancomycin resistance D-Ala-D-Ala dipeptidase VanX in Streptomyces toyocaensis, Escherichia coli and Synechocystis: attributes of catalytic efficiency, stereoselectivity and regulation with implications for function. Lessard IA, et al. Chem Biol, 1998 Sep. PMID 9751644
    4. Global gene expression profiling in Escherichia coli K12: effects of oxygen availability and ArcA. Salmon KA, et al. J Biol Chem, 2005 Apr 15. PMID 15699038
    5. Nitrogen regulatory protein C-controlled genes of Escherichia coli: scavenging as a defense against nitrogen limitation. Zimmer DP, et al. Proc Natl Acad Sci U S A, 2000 Dec 19. PMID 11121068, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables peptide transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in dipeptide transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in dipeptide transport NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in peptide transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in peptide transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of ATP-binding cassette (ABC) transporter complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    is_active_in outer membrane-bounded periplasmic space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in outer membrane-bounded periplasmic space IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in periplasmic space IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative D,D-dipeptide ABC transporter periplasmic binding protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1560931..1562481 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416004.1 putative D,D-dipeptide ABC transporter periplasmic binding protein [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416004.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7EJD9
      Conserved Domains (1) summary
      cd08512
      Location:28 → 499
      PBP2_NikA_DppA_OppA_like_7; The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold
    Nucleotide Protein
    Heading Accession and Version

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