dapB 4-hydroxy-tetrahydrodipicolinate reductase [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

Official Symbol: dapB
Official Full Name: 4-hydroxy-tetrahydrodipicolinate reductase
Primary source: ECOCYC:EG10206
Locus tag: b0031
See related: ASAP:ABE-0000112
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: ECK0032
Summary: A dapB mutant is not in the Keio collection; DAP auxotrophs require added DAP to grow and since no DAP was added during mutant construction, no auxotrophic mutants were recovered; dapB is not an essential gene (Baba, 2006). [More information is available at EcoGene: EG10206].
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NC_000913.3 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Degradation of the Escherichia coli Essential Proteins DapB and Dxr Results in Oxidative Stress, which Contributes to Lethality through Incomplete Base Excision Repair.
Title: Degradation of the Escherichia coli Essential Proteins DapB and Dxr Results in Oxidative Stress, which Contributes to Lethality through Incomplete Base Excision Repair.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables 4-hydroxy-tetrahydrodipicolinate reductase	IBA Inferred from Biological aspect of Ancestor more info
enables 4-hydroxy-tetrahydrodipicolinate reductase	IDA Inferred from Direct Assay more info	PubMed
enables 4-hydroxy-tetrahydrodipicolinate reductase	IEA Inferred from Electronic Annotation more info
enables NAD binding	IEA Inferred from Electronic Annotation more info
enables NADP binding	IEA Inferred from Electronic Annotation more info
enables identical protein binding	IDA Inferred from Direct Assay more info	PubMed
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within amino acid biosynthetic process	IDA Inferred from Direct Assay more info	PubMed
involved_in diaminopimelate biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within diaminopimelate biosynthetic process	IDA Inferred from Direct Assay more info	PubMed
involved_in diaminopimelate biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within diaminopimelate biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in lysine biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in lysine biosynthetic process via diaminopimelate	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytosol	HDA more info	PubMed
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed

NP_414572.1

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The following sections contain reference sequences that belong to a specific genome build. Explain