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    ftsP cell division protein FtsP [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 944982, updated on 3-Dec-2024

    Summary

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    Official Symbol
    ftsP
    Official Full Name
    cell division protein FtsP
    Primary source
    ECOCYC:EG11376
    Locus tag
    b3017
    See related
    ASAP:ABE-0009905
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3008; sufI; sui
    Summary
    SufI localizes to the septal ring in the dividing cell (Tarry (2009). [More information is available at EcoGene: EG11376]. FtsP (SufI) is a component of the cell division machinery that is required during stress conditions and may play a role in stabilizing the assembly of the divisome . [More information is available at EcoCyc: EG11376].
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    Genomic context

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    Sequence:
    NC_000913.3 (3161257..3162669, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene lipoprotein YqhH Neighboring gene radical SAM superfamily protein YgiQ Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase PlsC Neighboring gene DNA topoisomerase IV subunit A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Interconvertibility of lipid- and translocon-bound forms of the bacterial Tat precursor pre-SufI. Bageshwar UK, et al. Mol Microbiol, 2009 Oct. PMID 19732346, Free PMC Article
    2. An Escherichia coli twin-arginine signal peptide switches between helical and unstructured conformations depending on the hydrophobicity of the environment. San Miguel M, et al. Eur J Biochem, 2003 Aug. PMID 12899691
    3. Twin-arginine-dependent translocation of SufI in the absence of cytosolic helper proteins. Holzapfel E, et al. Biochemistry, 2009 Jun 16. PMID 19432418
    4. Transient ribosomal attenuation coordinates protein synthesis and co-translational folding. Zhang G, et al. Nat Struct Mol Biol, 2009 Mar. PMID 19198590
    5. The Escherichia coli cell division protein and model Tat substrate SufI (FtsP) localizes to the septal ring and has a multicopper oxidase-like structure. Tarry M, et al. J Mol Biol, 2009 Feb 20. PMID 19135451, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Cell division is antagonized by the activity of peptidoglycan endopeptidases that promote cell elongation.
      Title: Cell division is antagonized by the activity of peptidoglycan endopeptidases that promote cell elongation.
    2. This study showed that sufI is essential for the viability of E. coli cells subjected to various forms of stress, including oxidative stress and DNA damage.
      Title: Role of SufI (FtsP) in cell division of Escherichia coli: evidence for its involvement in stabilizing the assembly of the divisome.
    3. N-terminus verified by Edman degradation on mature peptide
      Title: Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables copper ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within FtsZ-dependent cytokinesis EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in FtsZ-dependent cytokinesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cell division IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to ionizing radiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to oxidative stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell division site IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cell division site IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in outer membrane-bounded periplasmic space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in outer membrane-bounded periplasmic space IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in outer membrane-bounded periplasmic space IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in periplasmic space IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cell division protein FtsP

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3161257..3162669 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417489.1 cell division protein FtsP [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417489.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376WUL6
      Conserved Domains (1) summary
      PRK10883
      Location:1 → 470
      PRK10883; FtsI repressor; Provisional
    Nucleotide Protein
    Heading Accession and Version

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