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    rpmA 50S ribosomal subunit protein L27 [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945190, updated on 3-Dec-2024

    Summary

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    Official Symbol
    rpmA
    Official Full Name
    50S ribosomal subunit protein L27
    Primary source
    ECOCYC:EG50002
    Locus tag
    b3185
    See related
    ASAP:ABE-0010468
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3174; rpz
    Summary
    The L27 protein is a component of the 50S subunit of the ribosome and may be an integral and functional component of the peptidyl transferase center. [More information is available at EcoCyc: EG50002].
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    Genomic context

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    Sequence:
    NC_000913.3 (3332862..3333119, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene GTPase ObgE Neighboring gene putative transporter YhbE Neighboring gene 50S ribosomal subunit protein L21 Neighboring gene all-trans-octaprenyl-diphosphate synthase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Activities of the peptidyl transferase center of ribosomes lacking protein L27. Maracci C, et al. RNA, 2015 Dec. PMID 26475831, Free PMC Article
    2. The primary structure of protein L27 from the peptidyl-tRNA binding site of Escherichia coli ribosomes. Chen R, et al. FEBS Lett, 1975 Nov 1. PMID 1225626
    3. Differential effects of replacing Escherichia coli ribosomal protein L27 with its homologue from Aquifex aeolicus. Maguire BA, et al. J Bacteriol, 2001 Nov. PMID 11673426, Free PMC Article
    4. Genes coding for ribosomal proteins S15, L21, and L27 map near argG in Escherichia coli. Kitakawa M, et al. J Bacteriol, 1979 Jun. PMID 378941, Free PMC Article
    5. Coexpression of Escherichia coli obgE, Encoding the Evolutionarily Conserved Obg GTPase, with Ribosomal Proteins L21 and L27. Maouche R, et al. J Bacteriol, 2016 Jul 1. PMID 27137500, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. obgE is cotranscribed with ribosomal protein genes rplU and rpmA.
      Title: Coexpression of Escherichia coli obgE, Encoding the Evolutionarily Conserved Obg GTPase, with Ribosomal Proteins L21 and L27.
    2. N-terminus verified by Edman degradation on mature peptide
      Title: A method for the chemical generation of N-terminal peptide sequence tags for rapid protein identification.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables rRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ribosome binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in assembly of large subunit precursor of preribosome IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in cytoplasmic translation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within cytosolic ribosome assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of ribosome biogenesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in regulation of cell growth IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in ribosomal large subunit assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in ribosomal large subunit assembly IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cytosolic large ribosomal subunit IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    50S ribosomal subunit protein L27

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3332862..3333119 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417652.1 50S ribosomal subunit protein L27 [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417652.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2X1MU05
      Conserved Domains (1) summary
      PRK05435
      Location:1 → 83
      rpmA; 50S ribosomal protein L27; Validated
    Nucleotide Protein
    Heading Accession and Version

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