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    ligB DNA ligase B [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948164, updated on 3-Dec-2024

    Summary

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    Official Symbol
    ligB
    Official Full Name
    DNA ligase B
    Primary source
    ECOCYC:EG11334
    Locus tag
    b3647
    See related
    ASAP:ABE-0011923
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3637; yicF
    Summary
    LigB is a NAD(+)-dependent DNA ligase . [More information is available at EcoCyc: EG11334].
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    Genomic context

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    Sequence:
    NC_000913.3 (3819488..3821170, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative RNase adaptor protein YicC Neighboring gene DNA damage-inducible protein D Neighboring gene PF03458 family inner membrane protein YicG Neighboring gene guanylate kinase Neighboring gene RNA polymerase subunit omega

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Escherichia coli DNA ligase B may mitigate damage from oxidative stress. Bodine TJ, et al. PLoS One, 2017. PMID 28700629, Free PMC Article
    2. Guanylate kinase of Escherichia coli K-12. Gentry D, et al. J Biol Chem, 1993 Jul 5. PMID 8390989
    3. DNA and RNA ligases: structural variations and shared mechanisms. Pascal JM. Curr Opin Struct Biol, 2008 Feb. PMID 18262407
    4. The majority of Escherichia coli mRNAs undergo post-transcriptional modification in exponentially growing cells. Mohanty BK, et al. Nucleic Acids Res, 2006. PMID 17040898, Free PMC Article
    5. DNA sequence and analysis of 136 kilobases of the Escherichia coli genome: organizational symmetry around the origin of replication. Burland V, et al. Genomics, 1993 Jun. PMID 7686882

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA ligase (NAD+) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA ligase (NAD+) activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA ligase (NAD+) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA ligation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in DNA ligation involved in DNA repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within DNA ligation involved in DNA repair IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in DNA metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DNA ligase B
    NP_418104.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3819488..3821170 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418104.2 DNA ligase B [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418104.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A1X3JA95
      Conserved Domains (1) summary
      PRK08097
      Location:1 → 560
      ligB; NAD-dependent DNA ligase LigB
    Nucleotide Protein
    Heading Accession and Version

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