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    hprS sensor histidine kinase HprS [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946487, updated on 3-Dec-2024

    Summary

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    Official Symbol
    hprS
    Official Full Name
    sensor histidine kinase HprS
    Primary source
    ECOCYC:G7056
    Locus tag
    b1968
    See related
    ASAP:ABE-0006531
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1964; yedV
    Summary
    [More information is available at EcoGene: EG14044]. YedV and YedW are predicted to function as a histidine kinase/response regulator pair of a two-component signal transduction system. [More information is available at EcoCyc: G7056].
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    Genomic context

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    Sequence:
    NC_000913.3 (2036794..2038152, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene protein/nucleic acid deglycase 1 Neighboring gene DNA-binding transcriptional dual regulator HprR Neighboring gene hydroxyisourate hydrolase/transthyretin-related protein Neighboring gene protein-L-methionine sulfoxide reductase catalytic subunit MsrP

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. HprSR Is a Reactive Chlorine Species-Sensing, Two-Component System in Escherichia coli. El Hajj S, et al. J Bacteriol, 2022 Feb 15. PMID 34898261, Free PMC Article
    2. Compilation of all genes encoding two-component phosphotransfer signal transducers in the genome of Escherichia coli. Mizuno T. DNA Res, 1997 Apr 28. PMID 9205844
    3. Transcriptional response of Escherichia coli to external copper. Yamamoto K, et al. Mol Microbiol, 2005 Apr. PMID 15773991
    4. Phenotype microarray analysis of Escherichia coli K-12 mutants with deletions of all two-component systems. Zhou L, et al. J Bacteriol, 2003 Aug. PMID 12897016, Free PMC Article
    5. Transcriptome analysis of all two-component regulatory system mutants of Escherichia coli K-12. Oshima T, et al. Mol Microbiol, 2002 Oct. PMID 12366850

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphorelay sensor kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphorelay sensor kinase activity RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity, transferring phosphorus-containing groups IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA damage response IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in phosphorelay signal transduction system IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in phosphorelay signal transduction system IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to copper ion IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to hypochlorite IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in signal transduction RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sensor histidine kinase HprS
    NP_416477.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2036794..2038152 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416477.1 sensor histidine kinase HprS [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416477.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7ELQ1, A0A8S7HZA5
      Conserved Domains (1) summary
      TIGR01386
      Location:3 → 449
      cztS_silS_copS; heavy metal sensor kinase
    Nucleotide Protein
    Heading Accession and Version

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