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    PRM2 pheromone-regulated protein PRM2 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854774, updated on 9-Dec-2024

    Summary

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    Official Symbol
    PRM2
    Official Full Name
    pheromone-regulated protein PRM2
    Primary source
    SGD:S000001299
    Locus tag
    YIL037C
    See related
    AllianceGenome:SGD:S000001299; FungiDB:YIL037C; VEuPathDB:YIL037C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in karyogamy involved in conjugation with cellular fusion. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See PRM2 in Genome Data Viewer
    Location:
    chromosome: IX
    Exon count:
    1
    Sequence:
    Chromosome: IX; NC_001141.2 (283029..284999, complement)

    Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene Ted1p Neighboring gene CCR4-NOT core subunit NOT3 Neighboring gene Cst6p Neighboring gene casein kinase 2 catalytic subunit CKA1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001141.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Role of transcription factor Kar4 in regulating downstream events in the Saccharomyces cerevisiae pheromone response pathway. Lahav R, et al. Mol Cell Biol, 2007 Feb. PMID 17101777, Free PMC Article
    2. The mating response cascade does not modulate changes in the steady-state level of target mRNAs through control of mRNA stability. Kitchen CM, et al. Yeast, 2009 May. PMID 19319831
    3. The undertranslated transcriptome reveals widespread translational silencing by alternative 5' transcript leaders. Law GL, et al. Genome Biol, 2005. PMID 16420678, Free PMC Article
    4. Prm1p, a pheromone-regulated multispanning membrane protein, facilitates plasma membrane fusion during yeast mating. Heiman MG, et al. J Cell Biol, 2000 Oct 30. PMID 11062271, Free PMC Article
    5. Functional analysis with a barcoder yeast gene overexpression system. Douglas AC, et al. G3 (Bethesda), 2012 Oct. PMID 23050238, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in karyogamy involved in conjugation with cellular fusion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pheromone-regulated protein PRM2
    NP_012227.3
    • Pheromone-regulated protein; predicted to have 4 transmembrane segments and a coiled coil domain; regulated by Ste12p; required for efficient nuclear fusion

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001141.2 Reference assembly

      Range
      283029..284999 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179387.3 → NP_012227.3  TPA: pheromone-regulated protein PRM2 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012227.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VVP5, P40534
      UniProtKB/TrEMBL
      G2WGA9, N1P0M3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P40534.1

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