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    CUE4 Cue4p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854871, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CUE4
    Official Full Name
    Cue4p
    Primary source
    SGD:S000004568
    Locus tag
    YML101C
    See related
    AllianceGenome:SGD:S000004568; FungiDB:YML101C; VEuPathDB:YML101C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable ubiquitin binding activity. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See CUE4 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (69735..70088, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Cac2p Neighboring gene uncharacterized protein Neighboring gene trehalose 6-phosphate synthase/phosphatase complex subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A ubiquitin-binding motif required for intramolecular monoubiquitylation, the CUE domain. Shih SC, et al. EMBO J, 2003 Mar 17. PMID 12628920, Free PMC Article
    2. A visual screen of protein localization during sporulation identifies new components of prospore membrane-associated complexes in budding yeast. Lam C, et al. Eukaryot Cell, 2014 Mar. PMID 24390141, Free PMC Article
    3. Mapping the functional yeast ABC transporter interactome. Snider J, et al. Nat Chem Biol, 2013 Sep. PMID 23831759, Free PMC Article
    4. Subcellular localization of the yeast proteome. Kumar A, et al. Genes Dev, 2002 Mar 15. PMID 11914276, Free PMC Article
    5. Identification of karyopherins involved in the nuclear import of RNA exosome subunit Rrp6 in Saccharomyces cerevisiae. Gonzales-Zubiate FA, et al. J Biol Chem, 2017 Jul 21. PMID 28539363, Free PMC Article

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables ubiquitin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum HDA PubMed 
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Cue4p
    NP_013607.1
    • hypothetical protein; has a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination; CUE4 has a paralog, CUE1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      69735..70088 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182462.1 → NP_013607.1  TPA: Cue4p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013607.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W0I3, Q04201
      UniProtKB/TrEMBL
      A6ZLW3, B3LLF7, C7GV83, C8ZEA2, G2WJV5, N1NXI4
      Conserved Domains (1) summary
      cd14424
      Location:77 → 112
      CUE_Cue1p_like; CUE domain found in yeast ubiquitin-binding protein CUE1 (Cue1p), CUE4 (Cue4p) and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q04201.1

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