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    2610008E11Rik RIKEN cDNA 2610008E11 gene [ Mus musculus (house mouse) ]

    Gene ID: 72128, updated on 9-Dec-2024

    Summary

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    Official Symbol
    2610008E11Rikprovided by MGI
    Official Full Name
    RIKEN cDNA 2610008E11 geneprovided by MGI
    Primary source
    MGI:MGI:1919378
    See related
    Ensembl:ENSMUSG00000060301 AllianceGenome:MGI:1919378
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in CNS E14 (RPKM 8.4), CNS E18 (RPKM 8.0) and 19 other tissues See more
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    Genomic context

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    See 2610008E11Rik in Genome Data Viewer
    Location:
    10 C1; 10 39.72 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (78900208..78933434, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (79064374..79097600, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_27238 Neighboring gene olfactory receptor family 7 subfamily A member 35 Neighboring gene STARR-seq mESC enhancer starr_27239 Neighboring gene predicted gene, 40712 Neighboring gene olfactory receptor family 7 subfamily A member 41 Neighboring gene STARR-positive B cell enhancer ABC_E3895 Neighboring gene vomeronasal 2, receptor 80 Neighboring gene STARR-seq mESC enhancer starr_27242 Neighboring gene STARR-seq mESC enhancer starr_27243 Neighboring gene vomeronasal 2, receptor 81

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
    2. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Clone Names

    • MGC90797

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC72128

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004362.2 → NP_001004362.2  uncharacterized protein LOC72128 isoform 1

      See identical proteins and their annotated locations for NP_001004362.2

      Status: VALIDATED

      Source sequence(s)
      AC104097, AK148309
      Consensus CDS
      CCDS35965.1
      UniProtKB/TrEMBL
      G3X964
      Related
      ENSMUSP00000044020.7, ENSMUST00000039271.7
      Conserved Domains (5) summary
      smart00349
      Location:10 → 69
      KRAB; krueppel associated box
      COG5048
      Location:299 → 644
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:529 → 549
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:10 → 49
      KRAB; KRAB box
      pfam13465
      Location:569 → 592
      zf-H2C2_2; Zinc-finger double domain

    2. NM_001359715.1 → NP_001346644.1  uncharacterized protein LOC72128 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AK148309, BC082302, BU703831
      Conserved Domains (3) summary
      smart00349
      Location:10 → 69
      KRAB; krueppel associated box
      COG5048
      Location:271 → 616
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:501 → 521
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. NM_001359717.1 → NP_001346646.1  uncharacterized protein LOC72128 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AK148309, BC082302, CN526042
      Conserved Domains (2) summary
      COG5048
      Location:135 → 480
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:365 → 385
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      78900208..78933434 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017314115.1 → XP_017169604.1  uncharacterized protein LOC72128 isoform X1

      Conserved Domains (2) summary
      COG5048
      Location:135 → 480
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:365 → 385
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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