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    Slc25a45 solute carrier family 25, member 45 [ Mus musculus (house mouse) ]

    Gene ID: 107375, updated on 3-Dec-2024

    Summary

    Official Symbol
    Slc25a45provided by MGI
    Official Full Name
    solute carrier family 25, member 45provided by MGI
    Primary source
    MGI:MGI:2147731
    See related
    Ensembl:ENSMUSG00000024818 AllianceGenome:MGI:2147731
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Located in mitochondrion. Is expressed in several structures, including alimentary system; hemolymphoid system; liver; and urinary system. Orthologous to human SLC25A45 (solute carrier family 25 member 45). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in duodenum adult (RPKM 85.7), small intestine adult (RPKM 41.3) and 14 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Slc25a45 in Genome Data Viewer
    Location:
    19 A; 19 4.34 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (5927828..5935796)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (5877801..5885768)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene nuclear paraspeckle assembly transcript 1 (non-protein coding) Neighboring gene STARR-seq mESC enhancer starr_45410 Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:5844330-5844513 Neighboring gene STARR-seq mESC enhancer starr_45411 Neighboring gene FERM domain containing 8, opposite strand Neighboring gene FERM domain containing 8 Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:5878208-5878317 Neighboring gene STARR-positive B cell enhancer ABC_E1522 Neighboring gene tigger transposable element derived 3 Neighboring gene double PHD fingers 2 Neighboring gene STARR-positive B cell enhancer ABC_E7628

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    solute carrier family 25 member 45

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001361973.1NP_001348902.1  solute carrier family 25 member 45 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC142098
      Consensus CDS
      CCDS29482.1
      UniProtKB/Swiss-Prot
      Q3TC75, Q3UZE9, Q8CFJ7, Q8VBZ7
      Related
      ENSMUSP00000121596.2, ENSMUST00000155697.8
      Conserved Domains (1) summary
      pfam00153
      Location:197288
      Mito_carr; Mitochondrial carrier protein
    2. NM_001361974.1NP_001348903.1  solute carrier family 25 member 45 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC142098
      Consensus CDS
      CCDS89319.1
      UniProtKB/TrEMBL
      A0A494BAQ4, D3Z5G2
      Related
      ENSMUSP00000117220.2, ENSMUST00000145200.8
      Conserved Domains (1) summary
      pfam00153
      Location:139230
      Mito_carr; Mitochondrial carrier protein
    3. NM_001425851.1NP_001412780.1  solute carrier family 25 member 45 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC142098
      UniProtKB/TrEMBL
      A0A494BAQ4, D3Z5G2
    4. NM_134154.4NP_598915.1  solute carrier family 25 member 45 isoform 1

      See identical proteins and their annotated locations for NP_598915.1

      Status: VALIDATED

      Source sequence(s)
      AC142098
      Consensus CDS
      CCDS29482.1
      UniProtKB/Swiss-Prot
      Q3TC75, Q3UZE9, Q8CFJ7, Q8VBZ7
      Related
      ENSMUSP00000025732.8, ENSMUST00000025732.14
      Conserved Domains (1) summary
      pfam00153
      Location:197288
      Mito_carr; Mitochondrial carrier protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      5927828..5935796
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036161393.1XP_036017286.1  solute carrier family 25 member 45 isoform X1

      UniProtKB/TrEMBL
      A0A494BAQ4, D3Z5G2
      Conserved Domains (1) summary
      pfam00153
      Location:139230
      Mito_carr; Mitochondrial carrier protein