U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    gpmA 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945068, updated on 3-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    gpmA
    Official Full Name
    2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
    Primary source
    ECOCYC:EG11699
    Locus tag
    b0755
    See related
    ASAP:ABE-0002563
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0744; gpm
    Summary
    HT_Cmplx25_Cyt: [More information is available at EcoGene: EG11699]. Regulation has been described . [More information is available at EcoCyc: EG11699].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (786843..787595, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene PF13985 family protein YbgS Neighboring gene 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive Neighboring gene galactose-1-epimerase Neighboring gene galactokinase Neighboring gene galactose-1-phosphate uridylyltransferase

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Evolution of bacterial phosphoglycerate mutases: non-homologous isofunctional enzymes undergoing gene losses, gains and lateral transfers. Foster JM, et al. PLoS One, 2010 Oct 26. PMID 21187861, Free PMC Article
    2. High resolution structure of the phosphohistidine-activated form of Escherichia coli cofactor-dependent phosphoglycerate mutase. Bond CS, et al. J Biol Chem, 2001 Feb 2. PMID 11038361
    3. Mechanistic implications for Escherichia coli cofactor-dependent phosphoglycerate mutase based on the high-resolution crystal structure of a vanadate complex. Bond CS, et al. J Mol Biol, 2002 Mar 8. PMID 11884145
    4. Bacterial defense against aging: role of the Escherichia coli ArcA regulator in gene expression, readjusted energy flux and survival during stasis. Nyström T, et al. EMBO J, 1996 Jul 1. PMID 8670822, Free PMC Article
    5. Phosphoglycerate mutases. Fothergill-Gilmore LA, et al. Biochem Soc Trans, 1990 Apr. PMID 2165930

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on mature peptide
      Title: Protein identification with N and C-terminal sequence tags in proteome projects.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables guanosine tetraphosphate binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables intramolecular phosphotransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphoglycerate mutase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within canonical glycolysis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in gluconeogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in glycolytic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
    NP_415276.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      786843..787595 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415276.1 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415276.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A192CIV1, A0AA36KVR0, Q1REH6
      Conserved Domains (1) summary
      PRK14115
      Location:4 → 250
      gpmA; 2,3-diphosphoglycerate-dependent phosphoglycerate mutase
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.