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    idnT L-idonate/5-ketogluconate/gluconate transporter [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948798, updated on 3-Dec-2024

    Summary

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    Official Symbol
    idnT
    Official Full Name
    L-idonate/5-ketogluconate/gluconate transporter
    Primary source
    ECOCYC:EG12539
    Locus tag
    b4265
    See related
    ASAP:ABE-0013969
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4258; gntW; yjgT
    Summary
    IT (Ion Transporter) superfamily (Prakash, 2003). [More information is available at EcoGene: EG12539]. IdnT is a probable L-idonate and D-gluconate transporter. [More information is available at EcoCyc: EG12539].
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    Genomic context

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    Sequence:
    NC_000913.3 (4491206..4492525, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF853 domain-containing protein YjgR Neighboring gene DNA-binding transcriptional dual regulator IdnR Neighboring gene 5-keto-D-gluconate 5-reductase Neighboring gene L-idonate 5-dehydrogenase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The mechanism of maintenance of electroneutrality during the transport of gluconate by E. coli. Robin A, et al. FEBS Lett, 1973 Oct 15. PMID 4585187
    2. Transcriptional organization and regulation of the L-idonic acid pathway (GntII system) in Escherichia coli. Bausch C, et al. J Bacteriol, 2004 Mar. PMID 14973046, Free PMC Article
    3. Sequence analysis of the GntII (subsidiary) system for gluconate metabolism reveals a novel pathway for L-idonic acid catabolism in Escherichia coli. Bausch C, et al. J Bacteriol, 1998 Jul. PMID 9658018, Free PMC Article
    4. Sequence and hydropathy profile analysis of two classes of secondary transporters. Lolkema JS, et al. Mol Membr Biol, 2005 May-Jun. PMID 16096261
    5. Domain structure and pore loops in the 2-hydroxycarboxylate transporter family. Lolkema JS. J Mol Microbiol Biotechnol, 2006. PMID 17114896

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables L-idonate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables L-idonate transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables gluconate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables gluconate transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables gluconate transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in D-gluconate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in L-idonate catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in L-idonate transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within L-idonate transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within carbohydrate transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in gluconate transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in gluconate transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    L-idonate/5-ketogluconate/gluconate transporter

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4491206..4492525 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418686.1 L-idonate/5-ketogluconate/gluconate transporter [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418686.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7F2H8
      Conserved Domains (1) summary
      TIGR00791
      Location:1 → 438
      gntP; gluconate transporter
    Nucleotide Protein
    Heading Accession and Version

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