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    Saxo2 stabilizer of axonemal microtubules 2 [ Mus musculus (house mouse) ]

    Gene ID: 330577, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Saxo2provided by MGI
    Official Full Name
    stabilizer of axonemal microtubules 2provided by MGI
    Primary source
    MGI:MGI:1914618
    See related
    Ensembl:ENSMUSG00000038570 AllianceGenome:MGI:1914618
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fam154b; D030069K18; 1700129I04Rik
    Summary
    Predicted to enable microtubule binding activity. Is active in nucleus. Is expressed in lateral ventricle choroid plexus; lung epithelium; nasal cavity respiratory epithelium; and nasopharynx epithelium. Orthologous to human SAXO2 (stabilizer of axonemal microtubules 2). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in testis adult (RPKM 8.1), lung adult (RPKM 0.7) and 7 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Saxo2 in Genome Data Viewer
    Location:
    7 D3; 7 47.25 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (82282166..82297777, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (82632960..82648561, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene SH3-domain GRB2-like 3 Neighboring gene predicted gene, 51492 Neighboring gene ADAMTS-like 3 Neighboring gene VISTA enhancer mm1514 Neighboring gene elongation factor like GTPase 1 Neighboring gene RIKEN cDNA 4933406J10 gene Neighboring gene STARR-seq mESC enhancer starr_19388 Neighboring gene predicted gene, 29796

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Stauber M, et al. Dev Biol, 2017 Mar 15. PMID 27914912
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in axonemal microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in centriole IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in ciliary basal body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in sperm flagellum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    stabilizer of axonemal microtubules 2
    Names
    family with sequence similarity 154, member B
    protein FAM154B
    stablizer of axonemal microtubules 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001415796.1 → NP_001402725.1  stabilizer of axonemal microtubules 2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC138270

    2. NM_177894.5 → NP_808562.3  stabilizer of axonemal microtubules 2 isoform 2

      See identical proteins and their annotated locations for NP_808562.3

      Status: VALIDATED

      Source sequence(s)
      AC138270
      Consensus CDS
      CCDS21409.1
      UniProtKB/Swiss-Prot
      G3X9C9, Q8BQB6
      Related
      ENSMUSP00000057993.4, ENSMUST00000056728.5

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      82282166..82297777 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011241834.3 → XP_011240136.1  stabilizer of axonemal microtubules 2 isoform X2

    2. XM_030242693.2 → XP_030098553.1  stabilizer of axonemal microtubules 2 isoform X1

    3. XM_030242694.1 → XP_030098554.1  stabilizer of axonemal microtubules 2 isoform X3

      UniProtKB/TrEMBL
      Q8CAI4
      Related
      ENSMUST00000151632.8
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BQB6.2 GenPept UniProtKB/Swiss-Prot:Q8BQB6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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