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    CG9649 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41727, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG9649provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038211
    Locus tag
    Dmel_CG9649
    See related
    AllianceGenome:FB:FBgn0038211
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG9649; SP55
    Summary
    Predicted to enable serine-type endopeptidase activity. Predicted to be involved in innate immune response and proteolysis. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG9649 in Genome Data Viewer
    Location:
    88A12-88A12; 3-54 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (14215459..14217882, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (10041181..10043604, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Dopamine 1-like receptor 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Circadian transcription contributes to core period determination in Drosophila. Kadener S, et al. PLoS Biol, 2008 May 20. PMID 18494558, Free PMC Article
    2. Identification of unannotated exons of low abundance transcripts in Drosophila melanogaster and cloning of a new serine protease gene upregulated upon injury. Maia RM, et al. BMC Genomics, 2007 Jul 24. PMID 17650329, Free PMC Article
    3. The ups and downs of daily life: profiling circadian gene expression in Drosophila. Etter PD, et al. Bioessays, 2002 Jun. PMID 12111731
    4. Damage sensing mediated by serine proteases Hayan and Persephone for Toll pathway activation in apoptosis-deficient flies. Nakano S, et al. PLoS Genet, 2023 Jun. PMID 37319131, Free PMC Article
    5. Inter- and intra-species variation in genome-wide gene expression of Drosophila in response to parasitoid wasp attack. Salazar-Jaramillo L, et al. BMC Genomics, 2017 Apr 27. PMID 28449654, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables endopeptidase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type endopeptidase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteolysis ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9649-PA
    NP_650343.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      14215459..14217882 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142086.4 → NP_650343.1  uncharacterized protein Dmel_CG9649 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650343.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A4V9W2, Q9VFM0
      Related
      FBpp0082363
      Conserved Domains (3) summary
      smart00020
      Location:259 → 497
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:257 → 498
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
      pfam16030
      Location:29 → 124
      GD_N; Serine protease gd N-terminus
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VFM0 Q9VFM0

    Gene LinkOut

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