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    CG10555 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31771, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10555provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030034
    Locus tag
    Dmel_CG10555
    See related
    AllianceGenome:FB:FBgn0030034
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG10555
    Summary
    Predicted to enable nuclear receptor coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in synovial sarcoma. Orthologous to human SS18L2 (SS18 like 2); SS18 (SS18 subunit of BAF chromatin remodeling complex); and SS18L1 (SS18L1 subunit of BAF chromatin remodeling complex). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10555 in Genome Data Viewer
    Location:
    7E6-7E6; 1-23 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (8398940..8404516)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (8292973..8298549)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene pseudo Neighboring gene Phosphatidylinositol glycan anchor biosynthesis class T Neighboring gene leg arista wing complex Neighboring gene TATA box binding protein-related factor 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Shep RNA-Binding Capacity Is Required for Antagonism of gypsy Chromatin Insulator Activity. Chen D, et al. G3 (Bethesda), 2019 Mar 7. PMID 30630880, Free PMC Article
    2. Selective sweeps in a 2-locus model for sex-ratio meiotic drive in Drosophila simulans. Derome N, et al. Mol Biol Evol, 2008 Feb. PMID 18071199
    3. BICRA, a SWI/SNF Complex Member, Is Associated with BAF-Disorder Related Phenotypes in Humans and Model Organisms. Barish S, et al. Am J Hum Genet, 2020 Dec 3. PMID 33232675, Free PMC Article
    4. Functional conservation of Rel binding sites in drosophilid genomes. Copley RR, et al. Genome Res, 2007 Sep. PMID 17785540, Free PMC Article
    5. Messenger RNA is a functional component of a chromatin insulator complex. Matzat LH, et al. EMBO Rep, 2013 Oct. PMID 23917615, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables nuclear receptor coactivator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10555-PA
    CG10555-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      8398940..8404516
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298087.1 → NP_001285016.1  uncharacterized protein Dmel_CG10555, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285016.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W3G1
      Conserved Domains (1) summary
      pfam05030
      Location:141 → 200
      SSXT; SSXT protein (N-terminal region)

    2. NM_132246.3 → NP_572474.2  uncharacterized protein Dmel_CG10555, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572474.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W3G1
      Related
      FBpp0071122
      Conserved Domains (1) summary
      pfam05030
      Location:141 → 200
      SSXT; SSXT protein (N-terminal region)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5U0Y6 Q5U0Y6
    Q95RN5 Q95RN5
    Q9W3G1 Q9W3G1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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