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    Lsp1alpha Larval serum protein 1 alpha [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32199, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Lsp1alphaprovided by FlyBase
    Official Full Name
    Larval serum protein 1 alphaprovided by FlyBase
    Primary source
    FLYBASE:FBgn0002562
    Locus tag
    Dmel_CG2559
    See related
    AllianceGenome:FB:FBgn0002562
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG2559; DmeLSP1a; Dmel\CG2559; Lsp; LSP 1; LSP-1; LSP-1 alpha; Lsp-1alpha; LSP-1alpha; Lsp1; LSP1; Lsp1-alpha; LSP1-alpha; LSP1alpha; LSP1ALPHA
    Summary
    Part of larval serum protein complex. Is expressed in adult heart and embryonic/larval fat body. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Lsp1alpha in Genome Data Viewer
    Location:
    11A12-11A12; 1-38 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (12490291..12492982)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (12384324..12387015)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Cuticular protein 11A Neighboring gene Meckel syndrome, type 1 Neighboring gene meduse

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The X-linked alpha-chain gene of Drosophila LSP-1 does not show dosage compensation. Roberts DB, et al. Nature, 1979 Aug 23. PMID 572919
    2. The LSP1-alpha gene of Drosophila melanogaster exhibits dosage compensation when it is relocated to a different site on the X chromosome. Ghosh S, et al. EMBO J, 1989 Apr. PMID 2501087, Free PMC Article
    3. The retrotransposon copia regulates Drosophila gene expression both positively and negatively. Bryant LA, et al. Nucleic Acids Res, 1991 Oct 25. PMID 1658733, Free PMC Article
    4. Cis-acting sequences sufficient for correct tissue and temporal specificity of larval serum protein 1 genes of Drosophila. Delaney SJ, et al. EMBO J, 1987 Dec 1. PMID 16453814, Free PMC Article
    5. Location of the LSP-1 Genes in Drosophila Species by IN SITU Hybridization. Brock HW, et al. Genetics, 1983 Jan. PMID 17246102, Free PMC Article

    See all (91) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data show that the non-dosage compensated Lsp1alpha gene of Drosophila melanogaster escapes acetylation by MOF in larval fat body nuclei, but is flanked by two dosage compensated genes.
      Title: The non-dosage compensated Lsp1alpha gene of Drosophila melanogaster escapes acetylation by MOF in larval fat body nuclei, but is flanked by two dosage compensated genes.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    part_of larval serum protein complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    larval serum protein 1 alpha
    Names
    CG2559-PA
    Lsp1alpha-PA
    larval serum protein
    larval serum protein one alpha

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      12490291..12492982
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078583.3 → NP_511138.2  larval serum protein 1 alpha [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_511138.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P11995, Q9VYM4
      Related
      FBpp0073484
      Conserved Domains (3) summary
      pfam00372
      Location:287 → 523
      Hemocyanin_M; Hemocyanin, copper containing domain
      pfam03722
      Location:32 → 154
      Hemocyanin_N; Hemocyanin, all-alpha domain
      pfam03723
      Location:532 → 782
      Hemocyanin_C; Hemocyanin, ig-like domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P11995.3 P11995

    Gene LinkOut

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