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    CG3526 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31277, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG3526provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0040355
    Locus tag
    Dmel_CG3526
    See related
    AllianceGenome:FB:FBgn0040355
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG3526; EG:BACR43E12.4
    Summary
    Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in synaptic signaling. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3526 in Genome Data Viewer
    Location:
    3C2-3C2; 1-2 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (2890768..2894232)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (2784801..2788265)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene kin of irre Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and functional analysis of CG3526 in spermatogenesis of Drosophila melanogaster. Hu Q, et al. Insect Sci, 2024 Feb. PMID 37465843
    2. Abundant conserved microRNA target sites in the 5'-untranslated region and coding sequence. Zhou X, et al. Genetica, 2009 Nov. PMID 19578934
    3. High-resolution mapping of heterochromatin redistribution in a Drosophila position-effect variegation model. Vogel MJ, et al. Epigenetics Chromatin, 2009 Jan 29. PMID 19178722, Free PMC Article
    4. From first base: the sequence of the tip of the X chromosome of Drosophila melanogaster, a comparison of two sequencing strategies. Benos PV, et al. Genome Res, 2001 May. PMID 11337470, Free PMC Article
    5. A large-scale, in vivo transcription factor screen defines bivalent chromatin as a key property of regulatory factors mediating Drosophila wing development. Schertel C, et al. Genome Res, 2015 Apr. PMID 25568052, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Identification and functional analysis of CG3526 in spermatogenesis of Drosophila melanogaster.
      Title: Identification and functional analysis of CG3526 in spermatogenesis of Drosophila melanogaster.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in synaptic signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3526-PA
    CG3526-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      2890768..2894232
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001103401.1 → NP_001096871.1  uncharacterized protein Dmel_CG3526, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001096871.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V488, Q8IRV4
      Conserved Domains (2) summary
      cd02338
      Location:22 → 70
      ZZ_PCMF_like; Zinc finger, ZZ type. Zinc finger present in potassium channel modulatory factor (PCMF) 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Human potassium channel ...
      pfam05605
      Location:91 → 141
      zf-Di19; Drought induced 19 protein (Di19), zinc-binding

    2. NM_166954.2 → NP_726832.2  uncharacterized protein Dmel_CG3526, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726832.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W4V2
      Conserved Domains (2) summary
      cd02338
      Location:30 → 78
      ZZ_PCMF_like; Zinc finger, ZZ type. Zinc finger present in potassium channel modulatory factor (PCMF) 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Human potassium channel ...
      pfam05605
      Location:99 → 149
      zf-Di19; Drought induced 19 protein (Di19), zinc-binding
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IRV4 Q8IRV4
    Q9NEG2 Q9NEG2
    Q9W4V2 Q9W4V2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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