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    cnir cornichon related [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33520, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cnirprovided by FlyBase
    Official Full Name
    cornichon relatedprovided by FlyBase
    Primary source
    FLYBASE:FBgn0243513
    Locus tag
    Dmel_CG17262
    See related
    AllianceGenome:FB:FBgn0243513
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG17262; Cnir; Dmel\CG17262
    Summary
    Predicted to enable signaling receptor binding activity. Involved in vesicle-mediated transport. Predicted to be active in COPII-coated ER to Golgi transport vesicle and endoplasmic reticulum membrane. Is expressed in adult head. Orthologous to human CNIH4 (cornichon family member 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See cnir in Genome Data Viewer
    Location:
    23C5-23C5; 2-8 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (3038826..3039812, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (3038826..3039812, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene beta4GalNAcTB pilot Neighboring gene uncharacterized protein Neighboring gene Seryl-tRNA synthetase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila Cornichon acts as cargo receptor for ER export of the TGFalpha-like growth factor Gurken. Bökel C, et al. Development, 2006 Feb. PMID 16396907
    2. Wun2-mediated integrin recycling promotes apoptotic cell clearance in Drosophila melanogaster. Gao N, et al. Cell Death Differ, 2022 Dec. PMID 35840760, Free PMC Article
    3. Golgi-Resident Gαo Promotes Protrusive Membrane Dynamics. Solis GP, et al. Cell, 2017 Aug 24. PMID 28803726
    4. Defense Mechanisms against Viral Infection in Drosophila: RNAi and Non-RNAi. Swevers L, et al. Viruses, 2018 May 1. PMID 29723993, Free PMC Article
    5. Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599810, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables signaling receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vesicle-mediated transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in COPII-coated ER to Golgi transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    cornichon related
    Names
    CG17262-PA
    Cni-related
    cnir-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      3038826..3039812 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134901.2 → NP_608745.1  cornichon related [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608745.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C4XVF7, Q9VQL3
      Related
      FBpp0077350
      Conserved Domains (1) summary
      pfam03311
      Location:8 → 133
      Cornichon; Cornichon protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VQL3 Q9VQL3

    Gene LinkOut

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