U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Flad2 Flavin adenine dinucleotide synthetase 2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34759, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Flad2provided by FlyBase
    Official Full Name
    Flavin adenine dinucleotide synthetase 2provided by FlyBase
    Primary source
    FLYBASE:FBgn0032522
    Locus tag
    Dmel_CG16848
    See related
    AllianceGenome:FB:FBgn0032522
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG16848; Dmel\CG16848; FBgn0032522
    Summary
    Predicted to enable FMN adenylyltransferase activity. Predicted to be involved in FAD biosynthetic process. Predicted to be active in cytosol. Orthologous to human FLAD1 (flavin adenine dinucleotide synthetase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Flad2 in Genome Data Viewer
    Location:
    34B11-34B11; 2-48 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (13412519..13413716)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (13412519..13413716)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR44600 Neighboring gene uncharacterized protein Neighboring gene Vitelline membrane 34Ca Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Analysis of a Drosophila amplicon in follicle cells highlights the diversity of metazoan replication origins. Kim JC, et al. Proc Natl Acad Sci U S A, 2011 Oct 4. PMID 21933960, Free PMC Article
    2. Assessment of genome-wide protein function classification for Drosophila melanogaster. Mi H, et al. Genome Res, 2003 Sep. PMID 12952880, Free PMC Article
    3. Identification of a mitochondrial target of thiazolidinedione insulin sensitizers (mTOT)--relationship to newly identified mitochondrial pyruvate carrier proteins. Colca JR, et al. PLoS One, 2013. PMID 23690925, Free PMC Article
    4. Steroid Signaling Establishes a Female Metabolic State and Regulates SREBP to Control Oocyte Lipid Accumulation. Sieber MH, et al. Curr Biol, 2015 Apr 20. PMID 25802149, Free PMC Article
    5. Dynamics of Dark-Fly Genome Under Environmental Selections. Izutsu M, et al. G3 (Bethesda), 2015 Dec 4. PMID 26637434, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables FMN adenylyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables FMN adenylyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in FAD biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in FAD biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in mitochondrial matrix ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    flavin adenine dinucleotide synthetase 2
    Names
    CG16848-PA
    Flad2-PA
    NP_609653.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      13412519..13413716
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135809.2 → NP_609653.1  flavin adenine dinucleotide synthetase 2 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609653.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MZ99, Q9VJY1
      Related
      FBpp0080079
      Conserved Domains (1) summary
      cd01713
      Location:57 → 202
      PAPS_reductase; This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MZ99 Q8MZ99
    Q9VJY1 Q9VJY1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools