U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG10465 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35488, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG10465provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033017
    Locus tag
    Dmel_CG10465
    See related
    AllianceGenome:FB:FBgn0033017
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG10465
    Summary
    Predicted to be involved in protein homooligomerization. Is expressed in organism. Used to study chromosome 16p11.2 deletion syndrome, 593-kb. Orthologous to several human genes including KCTD10 (potassium channel tetramerization domain containing 10). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG10465 in Genome Data Viewer
    Location:
    41E5-41E5; 2-55 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (5339706..5340995, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (1227211..1228500, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene d4 Neighboring gene super sex combs Neighboring gene uncharacterized protein Neighboring gene Intraflagellar transport 20 Neighboring gene Cytochrome c oxidase subunit 4-like

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Dissecting the complexity of CNV pathogenicity: insights from Drosophila and zebrafish models. Yusuff T, et al. Curr Opin Genet Dev, 2021 Jun. PMID 33812298, Free PMC Article
    2. Functional assessment of the "two-hit" model for neurodevelopmental defects in Drosophila and X. laevis. Pizzo L, et al. PLoS Genet, 2021 Apr. PMID 33819264, Free PMC Article
    3. Pervasive genetic interactions modulate neurodevelopmental defects of the autism-associated 16p11.2 deletion in Drosophila melanogaster. Iyer J, et al. Nat Commun, 2018 Jun 29. PMID 29959322, Free PMC Article
    4. A presynaptic ENaC channel drives homeostatic plasticity. Younger MA, et al. Neuron, 2013 Sep 18. PMID 23973209, Free PMC Article
    5. The Drosophila Small Conductance Calcium-Activated Potassium Channel Negatively Regulates Nociception. Walcott KCE, et al. Cell Rep, 2018 Sep 18. PMID 30231996, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    • Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in protein homooligomerization IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG10465-PA

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      5339706..5340995 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136321.3 → NP_610165.1  uncharacterized protein Dmel_CG10465 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610165.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JZ62
      Related
      FBpp0085430
      Conserved Domains (2) summary
      smart00225
      Location:20 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam02214
      Location:21 → 112
      BTB_2; BTB/POZ domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7JZ62 Q7JZ62

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools