U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG8298 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36282, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG8298provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033673
    Locus tag
    Dmel_CG8298
    See related
    AllianceGenome:FB:FBgn0033673
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG8298
    Summary
    Predicted to be involved in carbohydrate metabolic process. Predicted to be active in mitochondrion. Is expressed in adult head; embryonic brain; larval ventral nerve cord; and organism. Human ortholog(s) of this gene implicated in glycerol kinase deficiency. Orthologous to human GK (glycerol kinase); GK2 (glycerol kinase 2); and GK3 (glycerol kinase 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG8298 in Genome Data Viewer
    Location:
    48D5-48D5; 2-65 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (11989131..11992350)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (7876636..7879855)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Ribonucleoside diphosphate reductase small subunit Neighboring gene uncharacterized protein Neighboring gene rhomboid-7 Neighboring gene long non-coding RNA:CR45319 Neighboring gene long non-coding RNA:CR45318 Neighboring gene off-track Neighboring gene long non-coding RNA:CR44306

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Conserved family of glycerol kinase loci in Drosophila melanogaster. Martinez Agosto JA, et al. Mol Genet Metab, 2006 Aug. PMID 16545593, Free PMC Article
    2. Temporal reciprocity of miRNAs and their targets during the maternal-to-zygotic transition in Drosophila. Bushati N, et al. Curr Biol, 2008 Apr 8. PMID 18394895
    3. CRISPR/Cas9 mediated genetic resource for unknown kinase and phosphatase genes in Drosophila. Wu M, et al. Sci Rep, 2020 Apr 30. PMID 32355295, Free PMC Article
    4. A Drosophila protein-interaction map centered on cell-cycle regulators. Stanyon CA, et al. Genome Biol, 2004. PMID 15575970, Free PMC Article
    5. Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599810, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    NOT enables glycerol kinase activity IKR
    Inferred from Key Residues
    more info
    		 PubMed 
    NOT enables transferase activity IKR
    Inferred from Key Residues
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial outer membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG8298-PA
    CG8298-PC

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      11989131..11992350
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_165860.3 → NP_725098.2  uncharacterized protein Dmel_CG8298, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725098.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z8S0, Q7JY99
      Conserved Domains (2) summary
      cd07769
      Location:12 → 534
      FGGY_GK; Glycerol kinases; a subfamily of the FGGY family of carbohydrate kinases
      TIGR01311
      Location:21 → 543
      glycerol_kin; glycerol kinase

    2. NM_136874.3 → NP_610718.1  uncharacterized protein Dmel_CG8298, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610718.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z8S0, Q7JY99
      Related
      FBpp0087149
      Conserved Domains (2) summary
      cd07769
      Location:12 → 534
      FGGY_GK; Glycerol kinases; a subfamily of the FGGY family of carbohydrate kinases
      TIGR01311
      Location:21 → 543
      glycerol_kin; glycerol kinase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7JY99 Q7JY99

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous